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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1B2
All Species:
18.48
Human Site:
S51
Identified Species:
27.11
UniProt:
P21281
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21281
NP_001684.2
511
56501
S51
R
L
T
Y
K
T
V
S
G
V
N
G
P
L
V
Chimpanzee
Pan troglodytes
XP_001145161
513
56950
C45
R
V
T
Y
R
T
V
C
S
V
N
G
P
L
V
Rhesus Macaque
Macaca mulatta
XP_001100869
540
59473
S80
R
L
T
Y
K
T
V
S
G
V
N
G
P
L
V
Dog
Lupus familis
XP_543263
511
56560
S51
R
L
T
Y
K
T
V
S
G
V
N
G
P
L
V
Cat
Felis silvestris
Mouse
Mus musculus
NP_598918
513
56772
C45
R
V
T
Y
R
T
V
C
S
V
N
G
P
L
V
Rat
Rattus norvegicus
P62815
511
56532
S51
R
L
T
Y
K
T
V
S
G
V
N
G
P
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49712
453
50207
P34
T
R
D
F
L
S
Q
P
R
L
T
Y
K
T
V
Frog
Xenopus laevis
NP_001080613
511
56429
S50
R
L
T
Y
R
T
V
S
G
V
N
G
P
L
V
Zebra Danio
Brachydanio rerio
XP_002663572
509
56459
A50
R
L
T
Y
K
T
V
A
G
V
N
G
P
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P31409
490
54531
K43
L
V
I
L
D
E
V
K
F
P
K
F
A
E
I
Honey Bee
Apis mellifera
XP_624112
495
55126
K48
L
V
I
L
D
E
V
K
F
P
K
F
A
E
I
Nematode Worm
Caenorhab. elegans
Q19626
491
54732
K46
L
V
I
L
N
D
V
K
F
P
Q
F
S
E
I
Sea Urchin
Strong. purpuratus
XP_794151
487
54097
K40
L
V
I
L
D
N
V
K
F
P
K
F
A
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZN1
487
54286
Y41
E
K
V
K
G
P
K
Y
Q
E
I
V
N
I
R
Baker's Yeast
Sacchar. cerevisiae
P16140
517
57731
E42
N
G
P
L
V
I
L
E
K
V
K
F
P
R
Y
Red Bread Mold
Neurospora crassa
P11593
513
56790
R38
L
D
N
V
K
F
P
R
Y
N
E
I
V
T
L
Conservation
Percent
Protein Identity:
100
84.4
94.4
98.8
N.A.
83.4
99
N.A.
N.A.
84.7
92.5
92.9
N.A.
86.5
85.7
82
84.5
Protein Similarity:
100
90.8
94.4
99.4
N.A.
90.2
99.4
N.A.
N.A.
86.6
95.8
96.4
N.A.
90
90
89.2
89.2
P-Site Identity:
100
73.3
100
100
N.A.
73.3
100
N.A.
N.A.
6.6
93.3
93.3
N.A.
6.6
6.6
6.6
6.6
P-Site Similarity:
100
86.6
100
100
N.A.
86.6
100
N.A.
N.A.
26.6
100
100
N.A.
20
20
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
73.7
75.6
74.4
Protein Similarity:
N.A.
N.A.
N.A.
83.3
82.4
82.2
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
0
0
0
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
19
7
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
0
0
0
0
13
0
7
0
7
7
0
0
25
0
% E
% Phe:
0
0
0
7
0
7
0
0
25
0
0
32
0
0
0
% F
% Gly:
0
7
0
0
7
0
0
0
38
0
0
50
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
25
0
0
7
0
0
0
0
7
7
0
7
25
% I
% Lys:
0
7
0
7
38
0
7
25
7
0
25
0
7
0
0
% K
% Leu:
32
38
0
32
7
0
7
0
0
7
0
0
0
50
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
7
7
0
0
0
7
50
0
7
0
0
% N
% Pro:
0
0
7
0
0
7
7
7
0
25
0
0
57
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
7
0
7
0
0
0
0
% Q
% Arg:
50
7
0
0
19
0
0
7
7
0
0
0
0
7
7
% R
% Ser:
0
0
0
0
0
7
0
32
13
0
0
0
7
0
0
% S
% Thr:
7
0
50
0
0
50
0
0
0
0
7
0
0
13
0
% T
% Val:
0
38
7
7
7
0
75
0
0
57
0
7
7
0
57
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
50
0
0
0
7
7
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _