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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1B2
All Species:
56.97
Human Site:
T472
Identified Species:
83.56
UniProt:
P21281
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21281
NP_001684.2
511
56501
T472
Q
G
P
Y
E
N
R
T
V
F
E
T
L
D
I
Chimpanzee
Pan troglodytes
XP_001145161
513
56950
S466
Q
G
P
Y
E
N
R
S
V
F
E
S
L
D
L
Rhesus Macaque
Macaca mulatta
XP_001100869
540
59473
T501
Q
G
P
Y
E
N
R
T
V
F
E
T
L
D
I
Dog
Lupus familis
XP_543263
511
56560
T472
Q
G
P
Y
E
N
R
T
V
Y
E
T
L
D
I
Cat
Felis silvestris
Mouse
Mus musculus
NP_598918
513
56772
T466
Q
G
P
Y
E
N
R
T
V
F
E
S
L
D
L
Rat
Rattus norvegicus
P62815
511
56532
T472
Q
G
P
Y
E
N
R
T
V
Y
E
T
L
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49712
453
50207
W422
Y
E
T
L
D
I
G
W
Q
L
L
R
I
F
P
Frog
Xenopus laevis
NP_001080613
511
56429
T471
Q
G
P
Y
D
N
R
T
V
Y
E
T
L
D
I
Zebra Danio
Brachydanio rerio
XP_002663572
509
56459
T471
Q
G
A
Y
E
N
R
T
V
F
E
T
L
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P31409
490
54531
T452
Q
G
N
Y
E
N
R
T
V
F
E
S
L
D
I
Honey Bee
Apis mellifera
XP_624112
495
55126
T457
Q
G
S
Y
E
N
R
T
V
F
E
S
L
D
I
Nematode Worm
Caenorhab. elegans
Q19626
491
54732
S452
Q
G
H
Y
E
N
R
S
V
F
E
S
L
D
I
Sea Urchin
Strong. purpuratus
XP_794151
487
54097
S449
Q
G
N
Y
E
N
R
S
V
F
E
S
L
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZN1
487
54286
N449
Q
G
A
Y
D
T
R
N
I
F
Q
S
L
D
L
Baker's Yeast
Sacchar. cerevisiae
P16140
517
57731
T453
Q
G
A
Y
E
D
R
T
V
F
E
S
L
D
Q
Red Bread Mold
Neurospora crassa
P11593
513
56790
T447
Q
G
P
Y
E
S
R
T
I
F
E
S
L
D
L
Conservation
Percent
Protein Identity:
100
84.4
94.4
98.8
N.A.
83.4
99
N.A.
N.A.
84.7
92.5
92.9
N.A.
86.5
85.7
82
84.5
Protein Similarity:
100
90.8
94.4
99.4
N.A.
90.2
99.4
N.A.
N.A.
86.6
95.8
96.4
N.A.
90
90
89.2
89.2
P-Site Identity:
100
80
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
0
86.6
93.3
N.A.
86.6
86.6
80
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
100
93.3
N.A.
93.3
93.3
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
73.7
75.6
74.4
Protein Similarity:
N.A.
N.A.
N.A.
83.3
82.4
82.2
P-Site Identity:
N.A.
N.A.
N.A.
46.6
73.3
73.3
P-Site Similarity:
N.A.
N.A.
N.A.
80
86.6
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
19
7
0
0
0
0
0
0
0
94
0
% D
% Glu:
0
7
0
0
82
0
0
0
0
0
88
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
75
0
0
0
7
0
% F
% Gly:
0
94
0
0
0
0
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
13
0
0
0
7
0
63
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
7
0
0
0
0
0
7
7
0
94
0
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
75
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
94
0
0
0
0
0
0
0
7
0
7
0
0
0
7
% Q
% Arg:
0
0
0
0
0
0
94
0
0
0
0
7
0
0
0
% R
% Ser:
0
0
7
0
0
7
0
19
0
0
0
57
0
0
0
% S
% Thr:
0
0
7
0
0
7
0
69
0
0
0
38
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
82
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
94
0
0
0
0
0
19
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _