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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1B2
All Species:
30.61
Human Site:
Y39
Identified Species:
44.89
UniProt:
P21281
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21281
NP_001684.2
511
56501
Y39
A
L
A
V
S
R
N
Y
L
S
Q
P
R
L
T
Chimpanzee
Pan troglodytes
XP_001145161
513
56950
Y33
M
Q
A
V
T
R
N
Y
I
T
H
P
R
V
T
Rhesus Macaque
Macaca mulatta
XP_001100869
540
59473
Y68
A
L
A
V
S
R
N
Y
L
S
Q
P
R
L
T
Dog
Lupus familis
XP_543263
511
56560
Y39
A
L
A
V
S
R
N
Y
L
S
Q
P
R
L
T
Cat
Felis silvestris
Mouse
Mus musculus
NP_598918
513
56772
Y33
V
Q
A
V
T
R
N
Y
I
T
H
P
R
V
T
Rat
Rattus norvegicus
P62815
511
56532
Y39
A
L
A
V
S
R
N
Y
L
S
Q
P
R
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49712
453
50207
Q22
G
P
G
G
A
R
E
Q
A
A
A
L
T
R
D
Frog
Xenopus laevis
NP_001080613
511
56429
Y38
V
Q
A
V
S
R
D
Y
L
S
Q
P
R
L
T
Zebra Danio
Brachydanio rerio
XP_002663572
509
56459
Y38
V
L
A
V
T
R
D
Y
I
S
Q
P
R
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P31409
490
54531
G31
L
T
Y
K
T
V
S
G
V
N
G
P
L
V
I
Honey Bee
Apis mellifera
XP_624112
495
55126
G36
L
T
Y
K
T
V
S
G
V
N
G
P
L
V
I
Nematode Worm
Caenorhab. elegans
Q19626
491
54732
G34
L
I
Y
Q
T
V
C
G
V
N
G
P
L
V
I
Sea Urchin
Strong. purpuratus
XP_794151
487
54097
G28
L
T
Y
R
T
V
C
G
V
N
G
P
L
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZN1
487
54286
P29
T
V
S
G
V
A
G
P
L
V
I
L
E
K
V
Baker's Yeast
Sacchar. cerevisiae
P16140
517
57731
T30
K
P
R
L
N
Y
N
T
V
S
G
V
N
G
P
Red Bread Mold
Neurospora crassa
P11593
513
56790
G26
N
T
V
G
G
V
N
G
P
L
V
I
L
D
N
Conservation
Percent
Protein Identity:
100
84.4
94.4
98.8
N.A.
83.4
99
N.A.
N.A.
84.7
92.5
92.9
N.A.
86.5
85.7
82
84.5
Protein Similarity:
100
90.8
94.4
99.4
N.A.
90.2
99.4
N.A.
N.A.
86.6
95.8
96.4
N.A.
90
90
89.2
89.2
P-Site Identity:
100
53.3
100
100
N.A.
53.3
100
N.A.
N.A.
6.6
80
73.3
N.A.
6.6
6.6
6.6
6.6
P-Site Similarity:
100
80
100
100
N.A.
80
100
N.A.
N.A.
20
86.6
93.3
N.A.
40
40
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
73.7
75.6
74.4
Protein Similarity:
N.A.
N.A.
N.A.
83.3
82.4
82.2
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
50
0
7
7
0
0
7
7
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
13
0
0
0
0
0
0
7
7
% D
% Glu:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
7
19
7
0
7
32
0
0
32
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
19
0
7
7
0
0
25
% I
% Lys:
7
0
0
13
0
0
0
0
0
0
0
0
0
7
0
% K
% Leu:
25
32
0
7
0
0
0
0
38
7
0
13
32
38
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
7
0
50
0
0
25
0
0
7
0
7
% N
% Pro:
0
13
0
0
0
0
0
7
7
0
0
75
0
0
7
% P
% Gln:
0
19
0
7
0
0
0
7
0
0
38
0
0
0
0
% Q
% Arg:
0
0
7
7
0
57
0
0
0
0
0
0
50
7
0
% R
% Ser:
0
0
7
0
32
0
13
0
0
44
0
0
0
0
0
% S
% Thr:
7
25
0
0
44
0
0
7
0
13
0
0
7
0
50
% T
% Val:
19
7
7
50
7
32
0
0
32
7
7
7
0
38
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
25
0
0
7
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _