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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP6V1C1 All Species: 50
Human Site: Y143 Identified Species: 84.62
UniProt: P21283 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P21283 NP_001686.1 382 43942 Y143 L K S R A S A Y N N L K G N L
Chimpanzee Pan troglodytes XP_519896 355 40662 Y143 L K S R A S A Y N N L K G N L
Rhesus Macaque Macaca mulatta XP_001083973 364 41853 E136 K G N L Q N L E R K N A G S L
Dog Lupus familis XP_532295 382 43937 Y143 L K S R A S A Y N N L K G N L
Cat Felis silvestris
Mouse Mus musculus Q9Z1G3 382 43869 Y143 L K S R A S A Y N N L K G N L
Rat Rattus norvegicus Q5FVI6 382 43882 Y143 L K S R A S A Y N N L K G N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506621 382 43889 Y143 L K S R A S A Y N N L K G N L
Chicken Gallus gallus XP_418370 382 44122 Y143 L K A R A S A Y N N L K G N L
Frog Xenopus laevis Q5XH14 382 43976 Y143 L K A R A S A Y N N L K G N L
Zebra Danio Brachydanio rerio Q7T385 383 44296 Y143 L K A R A S A Y N N L K G N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V7N5 836 92372 Y592 L K T K S Q A Y N N L K G N L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XXU9 384 43440 Y145 L K V K S L T Y N N L K N A L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SDS7 375 42601 Y143 L K V R V A E Y N N I R G Q L
Baker's Yeast Sacchar. cerevisiae P31412 392 44170 Y152 V R A T Y A N Y N S A K T N L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.4 95.2 99.2 N.A. 98.1 97.9 N.A. 96 94.5 94.2 88.2 N.A. 30.6 N.A. 56.2 N.A.
Protein Similarity: 100 92.6 95.2 99.7 N.A. 99.7 100 N.A. 98.9 98.1 98.4 94.5 N.A. 39.4 N.A. 75.2 N.A.
P-Site Identity: 100 100 13.3 100 N.A. 100 100 N.A. 100 93.3 93.3 93.3 N.A. 73.3 N.A. 53.3 N.A.
P-Site Similarity: 100 100 33.3 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 93.3 N.A. 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 39.7 34.6 N.A.
Protein Similarity: N.A. N.A. N.A. 58.9 54.8 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 29 0 65 15 72 0 0 0 8 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 0 0 0 0 0 0 0 86 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 8 86 0 15 0 0 0 0 0 8 0 86 0 0 0 % K
% Leu: 86 0 0 8 0 8 8 0 0 0 79 0 0 0 100 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 8 8 0 93 86 8 0 8 79 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 8 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 8 0 72 0 0 0 0 8 0 0 8 0 0 0 % R
% Ser: 0 0 43 0 15 65 0 0 0 8 0 0 0 8 0 % S
% Thr: 0 0 8 8 0 0 8 0 0 0 0 0 8 0 0 % T
% Val: 8 0 15 0 8 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 93 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _