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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1C1
All Species:
46.97
Human Site:
Y253
Identified Species:
79.49
UniProt:
P21283
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21283
NP_001686.1
382
43942
Y253
F
I
V
R
D
F
Q
Y
N
E
E
E
M
K
A
Chimpanzee
Pan troglodytes
XP_519896
355
40662
H239
K
A
V
D
D
F
R
H
K
A
R
E
N
K
F
Rhesus Macaque
Macaca mulatta
XP_001083973
364
41853
Y235
F
I
V
R
D
F
Q
Y
N
E
E
E
M
K
A
Dog
Lupus familis
XP_532295
382
43937
Y253
F
I
V
R
D
F
Q
Y
N
E
E
E
M
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1G3
382
43869
Y253
F
I
V
R
D
F
Q
Y
N
E
E
E
M
K
A
Rat
Rattus norvegicus
Q5FVI6
382
43882
Y253
F
I
V
R
D
F
Q
Y
N
E
E
E
M
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506621
382
43889
Y253
F
I
V
R
D
F
Q
Y
N
E
E
E
M
K
A
Chicken
Gallus gallus
XP_418370
382
44122
Y253
F
L
V
R
D
F
Q
Y
N
E
E
E
M
K
A
Frog
Xenopus laevis
Q5XH14
382
43976
Y253
F
V
V
R
D
F
Q
Y
N
E
E
E
M
K
A
Zebra Danio
Brachydanio rerio
Q7T385
383
44296
Y253
F
T
V
R
D
F
Q
Y
N
E
E
E
M
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7N5
836
92372
Y702
F
I
V
R
D
F
V
Y
N
E
E
E
L
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XXU9
384
43440
Y255
F
I
V
R
D
F
V
Y
D
E
E
T
L
K
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SDS7
375
42601
Q252
F
Q
V
R
D
F
E
Q
S
V
E
A
Q
E
T
Baker's Yeast
Sacchar. cerevisiae
P31412
392
44170
Y262
F
I
P
R
E
F
N
Y
S
E
E
L
I
D
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
95.2
99.2
N.A.
98.1
97.9
N.A.
96
94.5
94.2
88.2
N.A.
30.6
N.A.
56.2
N.A.
Protein Similarity:
100
92.6
95.2
99.7
N.A.
99.7
100
N.A.
98.9
98.1
98.4
94.5
N.A.
39.4
N.A.
75.2
N.A.
P-Site Identity:
100
33.3
100
100
N.A.
100
93.3
N.A.
100
93.3
93.3
93.3
N.A.
80
N.A.
73.3
N.A.
P-Site Similarity:
100
46.6
100
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
86.6
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.7
34.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.9
54.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
8
0
8
0
8
79
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
93
0
0
0
8
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
8
0
8
0
0
86
93
79
0
8
0
% E
% Phe:
93
0
0
0
0
100
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
65
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
8
0
0
0
0
72
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
0
8
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
65
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
72
0
0
0
8
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
65
8
0
0
0
0
8
0
8
% Q
% Arg:
0
0
0
93
0
0
8
0
0
0
8
0
0
8
0
% R
% Ser:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% T
% Val:
0
8
93
0
0
0
15
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
86
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _