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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FLNA
All Species:
22.42
Human Site:
S440
Identified Species:
70.48
UniProt:
P21333
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21333
NP_001104026.1
2647
280739
S440
Q
L
E
A
R
G
D
S
T
Y
R
C
S
Y
Q
Chimpanzee
Pan troglodytes
XP_001173963
2623
280682
C416
K
G
N
Q
V
Y
R
C
V
Y
K
P
M
Q
P
Rhesus Macaque
Macaca mulatta
XP_001091073
2647
280579
S440
Q
L
E
A
R
G
D
S
T
Y
R
C
T
Y
Q
Dog
Lupus familis
XP_538205
2638
279885
S440
Q
L
E
A
R
G
D
S
T
Y
R
C
S
Y
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTM8
2647
281175
S440
Q
L
E
A
R
G
D
S
T
Y
R
C
S
Y
Q
Rat
Rattus norvegicus
NP_001128071
2639
280476
S440
Q
L
E
A
R
G
D
S
T
Y
R
C
S
Y
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508334
2693
287074
S495
Q
L
E
D
K
G
N
S
T
Y
R
C
T
Y
K
Chicken
Gallus gallus
NP_989905
2610
272931
C428
R
G
D
G
A
F
R
C
S
Y
R
P
T
A
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.4
99.2
97.6
N.A.
97.3
97
N.A.
87.6
74.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
82.2
99.6
98.3
N.A.
98.4
98.1
N.A.
93.5
85.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
100
N.A.
100
100
N.A.
66.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
93.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
63
13
0
0
0
0
0
0
0
0
13
0
% A
% Cys:
0
0
0
0
0
0
0
25
0
0
0
75
0
0
0
% C
% Asp:
0
0
13
13
0
0
63
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
75
0
0
0
0
0
0
0
0
0
0
0
13
% E
% Phe:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
25
0
13
0
75
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
13
0
0
0
13
0
0
0
0
0
13
0
0
0
13
% K
% Leu:
0
75
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% M
% Asn:
0
0
13
0
0
0
13
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
13
% P
% Gln:
75
0
0
13
0
0
0
0
0
0
0
0
0
13
63
% Q
% Arg:
13
0
0
0
63
0
25
0
0
0
88
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
75
13
0
0
0
50
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
75
0
0
0
38
0
0
% T
% Val:
0
0
0
0
13
0
0
0
13
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
13
0
0
0
100
0
0
0
75
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _