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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB4
All Species:
8.79
Human Site:
T34
Identified Species:
16.11
UniProt:
P21439
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21439
NP_000434.1
1286
141523
T34
S
K
Q
K
R
K
K
T
K
T
V
K
M
I
G
Chimpanzee
Pan troglodytes
XP_001160982
1599
175326
T346
S
K
Q
K
R
K
K
T
K
T
V
K
M
I
G
Rhesus Macaque
Macaca mulatta
NP_001028059
1283
141504
S35
K
E
R
K
P
T
V
S
V
F
S
M
F
R
Y
Dog
Lupus familis
XP_539461
1269
140189
I36
Q
A
V
G
P
I
E
I
F
R
F
A
N
G
L
Cat
Felis silvestris
Mouse
Mus musculus
P21440
1276
140314
V34
G
R
E
K
K
K
K
V
N
L
I
G
L
L
T
Rat
Rattus norvegicus
Q08201
1278
140637
V34
S
R
E
K
K
K
K
V
N
L
I
G
P
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508941
1368
147746
M127
N
N
R
G
G
E
E
M
K
K
S
S
M
V
S
Chicken
Gallus gallus
XP_418636
1307
144961
P52
C
S
E
D
K
K
K
P
E
K
M
N
M
V
S
Frog
Xenopus laevis
NP_001081394
1287
141487
T43
F
K
K
K
K
E
K
T
E
K
P
P
K
V
G
Zebra Danio
Brachydanio rerio
Q56A55
714
77317
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q00748
1302
143766
F39
A
F
L
K
L
F
R
F
S
T
Y
G
E
I
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34712
1321
145045
E54
K
I
T
R
D
A
K
E
E
V
V
N
K
V
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FWX7
1278
137648
E35
T
K
K
E
E
K
S
E
E
K
A
N
T
V
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.9
75.8
53.9
N.A.
90.2
90.6
N.A.
67.6
70
67
25.1
N.A.
43
N.A.
43.1
N.A.
Protein Similarity:
100
79.4
86.4
73.4
N.A.
95.1
95.2
N.A.
80.9
83.6
80.9
36.7
N.A.
61.6
N.A.
61.2
N.A.
P-Site Identity:
100
100
6.6
0
N.A.
20
26.6
N.A.
13.3
20
33.3
0
N.A.
26.6
N.A.
13.3
N.A.
P-Site Similarity:
100
100
26.6
6.6
N.A.
60
60
N.A.
46.6
53.3
66.6
0
N.A.
40
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
8
0
0
0
0
8
8
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
24
8
8
16
16
16
31
0
0
0
8
0
0
% E
% Phe:
8
8
0
0
0
8
0
8
8
8
8
0
8
0
0
% F
% Gly:
8
0
0
16
8
0
0
0
0
0
0
24
0
8
31
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
0
8
0
0
16
0
0
24
0
% I
% Lys:
16
31
16
54
31
47
54
0
24
31
0
16
16
0
0
% K
% Leu:
0
0
8
0
8
0
0
0
0
16
0
0
8
16
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
8
8
31
0
0
% M
% Asn:
8
8
0
0
0
0
0
0
16
0
0
24
8
0
0
% N
% Pro:
0
0
0
0
16
0
0
8
0
0
8
8
8
0
8
% P
% Gln:
8
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
16
16
8
16
0
8
0
0
8
0
0
0
8
0
% R
% Ser:
24
8
0
0
0
0
8
8
8
0
16
8
0
0
24
% S
% Thr:
8
0
8
0
0
8
0
24
0
24
0
0
8
0
16
% T
% Val:
0
0
8
0
0
0
8
16
8
8
24
0
0
39
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _