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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNFAIP3 All Species: 36.06
Human Site: S217 Identified Species: 79.33
UniProt: P21580 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P21580 NP_006281.1 790 89614 S217 I S D K M L R S L E S G S N F
Chimpanzee Pan troglodytes XP_527515 976 109981 S409 I S D K M L R S L E S G S N F
Rhesus Macaque Macaca mulatta XP_001096105 790 89485 S217 I S D K M L R S L E S G S N F
Dog Lupus familis XP_541123 790 89438 S217 I S D K M L R S L E S G S N F
Cat Felis silvestris
Mouse Mus musculus Q60769 775 87577 S217 I S D K M L R S L E S G S N F
Rat Rattus norvegicus XP_001060914 814 91923 S254 I S D K M L R S L E S G S N F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509168 792 89556 S218 I S D K M L R S L E S G S S F
Chicken Gallus gallus XP_423720 937 103557 R290 V V A D T M L R D S G G E A F
Frog Xenopus laevis NP_001087109 781 89266 S218 L A D N V M R S L E S G S S F
Zebra Danio Brachydanio rerio XP_692922 762 86249 S219 I A D Q V L R S M K S G S S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795196 1187 131959 R235 I L A E N M W R D A A G K S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80 98.2 90.2 N.A. 88.2 85.1 N.A. 76.8 22.6 55.8 48.4 N.A. N.A. N.A. N.A. 24.3
Protein Similarity: 100 80.1 98.8 95.1 N.A. 92.7 89.5 N.A. 85.2 38 69.4 64.6 N.A. N.A. N.A. N.A. 37
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 13.3 60 60 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 26.6 93.3 100 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 19 0 0 0 0 0 0 10 10 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 82 10 0 0 0 0 19 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 73 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 91 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 10 100 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 82 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 64 0 0 0 0 0 10 0 0 10 0 0 % K
% Leu: 10 10 0 0 0 73 10 0 73 0 0 0 0 0 10 % L
% Met: 0 0 0 0 64 28 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 10 0 0 0 0 0 0 0 0 55 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 82 19 0 0 0 0 0 0 0 % R
% Ser: 0 64 0 0 0 0 0 82 0 10 82 0 82 37 0 % S
% Thr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % T
% Val: 10 10 0 0 19 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _