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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNFAIP3 All Species: 16.36
Human Site: S376 Identified Species: 36
UniProt: P21580 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P21580 NP_006281.1 790 89614 S376 A Q N P M E P S V P Q L S L M
Chimpanzee Pan troglodytes XP_527515 976 109981 S568 A Q N P M E P S V P Q L S L M
Rhesus Macaque Macaca mulatta XP_001096105 790 89485 S376 A Q N P M E S S L P Q L S L M
Dog Lupus familis XP_541123 790 89438 S376 A Q N P L E P S V P Q L S L M
Cat Felis silvestris
Mouse Mus musculus Q60769 775 87577 H368 D Q A R R A A H A Q N P L E P
Rat Rattus norvegicus XP_001060914 814 91923 A406 Q G R R G A H A Q N P L E A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509168 792 89556 L378 R N R L K L S L S Q L S L M D
Chicken Gallus gallus XP_423720 937 103557 A477 K E K D K K R A D S V A N K L
Frog Xenopus laevis NP_001087109 781 89266 L373 R R T R L E T L L P Q L S L V
Zebra Danio Brachydanio rerio XP_692922 762 86249 S377 S Q R P P P F S V S Q L S L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795196 1187 131959 P653 L G F L D S S P P R E I A V T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80 98.2 90.2 N.A. 88.2 85.1 N.A. 76.8 22.6 55.8 48.4 N.A. N.A. N.A. N.A. 24.3
Protein Similarity: 100 80.1 98.8 95.1 N.A. 92.7 89.5 N.A. 85.2 38 69.4 64.6 N.A. N.A. N.A. N.A. 37
P-Site Identity: 100 100 86.6 93.3 N.A. 6.6 6.6 N.A. 0 0 40 53.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 93.3 100 N.A. 6.6 13.3 N.A. 6.6 33.3 66.6 66.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 37 0 10 0 0 19 10 19 10 0 0 10 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 10 10 0 0 0 10 0 0 0 0 0 10 % D
% Glu: 0 10 0 0 0 46 0 0 0 0 10 0 10 10 0 % E
% Phe: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 19 0 0 10 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % I
% Lys: 10 0 10 0 19 10 0 0 0 0 0 0 0 10 0 % K
% Leu: 10 0 0 19 19 10 0 19 19 0 10 64 19 55 10 % L
% Met: 0 0 0 0 28 0 0 0 0 0 0 0 0 10 37 % M
% Asn: 0 10 37 0 0 0 0 0 0 10 10 0 10 0 0 % N
% Pro: 0 0 0 46 10 10 28 10 10 46 10 10 0 0 10 % P
% Gln: 10 55 0 0 0 0 0 0 10 19 55 0 0 0 0 % Q
% Arg: 19 10 28 28 10 0 10 0 0 10 0 0 0 0 0 % R
% Ser: 10 0 0 0 0 10 28 46 10 19 0 10 55 0 10 % S
% Thr: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 0 37 0 10 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _