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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNFAIP3 All Species: 28.79
Human Site: S568 Identified Species: 63.33
UniProt: P21580 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P21580 NP_006281.1 790 89614 S568 Q R S K S D P S R L V R S P S
Chimpanzee Pan troglodytes XP_527515 976 109981 S760 Q R S K S D P S Q L V R S P S
Rhesus Macaque Macaca mulatta XP_001096105 790 89485 S568 Q R S K S D P S Q L V R S P S
Dog Lupus familis XP_541123 790 89438 S568 Q R S K S D P S Q L I Q S L S
Cat Felis silvestris
Mouse Mus musculus Q60769 775 87577 S553 Q R S K S D P S Q L I Q S L T
Rat Rattus norvegicus XP_001060914 814 91923 S592 Q R S K S D P S Q L I Q S L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509168 792 89556 S569 Q R S R S D P S Q L M Q S F L
Chicken Gallus gallus XP_423720 937 103557 A705 L L R Q F P A A F G F T E A Y
Frog Xenopus laevis NP_001087109 781 89266 L558 L S R S L I P L S D L E G G H
Zebra Danio Brachydanio rerio XP_692922 762 86249 G569 S V W A E R S G Q T W Q T P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795196 1187 131959 S892 V Q Q A S E P S Q V A R A S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80 98.2 90.2 N.A. 88.2 85.1 N.A. 76.8 22.6 55.8 48.4 N.A. N.A. N.A. N.A. 24.3
Protein Similarity: 100 80.1 98.8 95.1 N.A. 92.7 89.5 N.A. 85.2 38 69.4 64.6 N.A. N.A. N.A. N.A. 37
P-Site Identity: 100 93.3 93.3 73.3 N.A. 66.6 66.6 N.A. 60 0 6.6 6.6 N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 86.6 13.3 13.3 33.3 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 0 0 10 10 0 0 10 0 10 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 64 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 10 10 0 0 0 0 0 10 10 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 10 0 10 0 0 10 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 10 0 0 10 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 28 0 0 0 0 % I
% Lys: 0 0 0 55 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 19 10 0 0 10 0 0 10 0 64 10 0 0 28 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 82 0 0 0 0 0 0 37 0 % P
% Gln: 64 10 10 10 0 0 0 0 73 0 0 46 0 0 0 % Q
% Arg: 0 64 19 10 0 10 0 0 10 0 0 37 0 0 0 % R
% Ser: 10 10 64 10 73 0 10 73 10 0 0 0 64 10 46 % S
% Thr: 0 0 0 0 0 0 0 0 0 10 0 10 10 0 19 % T
% Val: 10 10 0 0 0 0 0 0 0 10 28 0 0 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _