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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPHA1 All Species: 27.58
Human Site: Y739 Identified Species: 67.41
UniProt: P21709 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P21709 NP_005223.4 976 108067 Y739 G I A S G M N Y L S N H N Y V
Chimpanzee Pan troglodytes P0C0K6 1020 110674 V778 L V A M Q R G V A A A M Q Y L
Rhesus Macaque Macaca mulatta XP_001090564 978 108213 Y741 G I A S G M N Y L S N H N Y V
Dog Lupus familis XP_539851 1002 110021 Y765 G I A S G M N Y L S D H N Y V
Cat Felis silvestris
Mouse Mus musculus Q60750 977 108559 C740 G I A S G M N C L S G H N Y V
Rat Rattus norvegicus P54759 998 111935 Y748 G I A A G M R Y L A D M G Y V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519951 973 108448 Y726 G I A A G M K Y L A N M N Y V
Chicken Gallus gallus Q07496 986 109464 Y736 G I G S G M K Y L S D M S Y V
Frog Xenopus laevis Q91845 986 109822 Y735 G I G S G M K Y L S D M S Y V
Zebra Danio Brachydanio rerio O13146 981 109636 Y741 G I A A G M Q Y L S E M N Y V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.6 96.8 86.8 N.A. 88.3 44.2 N.A. 48.7 45.1 44.9 45.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 54.4 98.4 91 N.A. 92.5 61.1 N.A. 65.4 62.8 62.6 62.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 93.3 N.A. 86.6 60 N.A. 73.3 66.6 66.6 73.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 33.3 100 100 N.A. 86.6 80 N.A. 86.6 80 80 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 80 30 0 0 0 0 10 30 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 40 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 90 0 20 0 90 0 10 0 0 0 10 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 40 0 0 0 % H
% Ile: 0 90 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 30 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 0 0 0 90 0 0 0 0 0 10 % L
% Met: 0 0 0 10 0 90 0 0 0 0 0 60 0 0 0 % M
% Asn: 0 0 0 0 0 0 40 0 0 0 30 0 60 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 10 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 60 0 0 0 0 0 70 0 0 20 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 90 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 80 0 0 0 0 0 100 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _