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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD1
All Species:
36.36
Human Site:
S127
Identified Species:
66.67
UniProt:
P21728
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21728
NP_000785.1
446
49293
S127
D
R
Y
W
A
I
S
S
P
F
R
Y
E
R
K
Chimpanzee
Pan troglodytes
XP_528711
477
53003
R144
D
R
Y
W
A
I
S
R
P
F
R
Y
V
R
K
Rhesus Macaque
Macaca mulatta
O77680
446
49274
S127
D
R
Y
W
A
I
S
S
P
F
R
Y
E
R
K
Dog
Lupus familis
XP_546227
446
49338
S127
D
R
Y
W
A
I
S
S
P
F
R
Y
E
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61616
446
49594
S126
D
R
Y
W
A
I
S
S
P
F
Q
Y
E
R
K
Rat
Rattus norvegicus
P18901
446
49410
S126
D
R
Y
W
A
I
S
S
P
F
Q
Y
E
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521446
353
37571
V59
G
L
D
R
Y
W
A
V
S
S
P
F
G
Y
Q
Chicken
Gallus gallus
NP_001138320
451
50438
S126
D
R
Y
W
A
I
S
S
P
F
R
Y
E
R
K
Frog
Xenopus laevis
P42289
451
50531
S126
D
R
Y
W
A
I
S
S
P
F
R
Y
E
R
K
Zebra Danio
Brachydanio rerio
NP_001129448
446
49800
S125
D
R
Y
W
A
I
S
S
P
F
R
Y
E
R
K
Tiger Blowfish
Takifugu rubipres
P53452
459
51062
S127
D
R
Y
W
A
I
S
S
P
F
R
Y
E
R
K
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011595
402
44536
C108
W
I
A
F
D
V
M
C
S
T
A
S
I
L
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198071
459
51464
K154
D
R
Y
W
A
I
T
K
P
F
E
Y
Q
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.1
99.7
95.5
N.A.
91.2
90.3
N.A.
42.8
81.3
80.2
72.8
70.1
N.A.
35.4
N.A.
42.2
Protein Similarity:
100
70
99.7
97.7
N.A.
94.1
93.5
N.A.
56
88.4
86.6
83.1
79.7
N.A.
51.5
N.A.
56.4
P-Site Identity:
100
86.6
100
100
N.A.
93.3
93.3
N.A.
0
100
100
100
100
N.A.
0
N.A.
66.6
P-Site Similarity:
100
86.6
100
100
N.A.
100
100
N.A.
20
100
100
100
100
N.A.
13.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
85
0
8
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
85
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
8
0
70
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
85
0
8
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
85
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
85
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
85
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
16
0
8
0
8
% Q
% Arg:
0
85
0
8
0
0
0
8
0
0
62
0
0
77
0
% R
% Ser:
0
0
0
0
0
0
77
70
16
8
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
8
0
0
0
0
8
0
0
% V
% Trp:
8
0
0
85
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
85
0
8
0
0
0
0
0
0
85
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _