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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD1
All Species:
12.12
Human Site:
S172
Identified Species:
22.22
UniProt:
P21728
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21728
NP_000785.1
446
49293
S172
K
A
K
P
T
S
P
S
D
G
N
A
T
S
L
Chimpanzee
Pan troglodytes
XP_528711
477
53003
G189
R
D
Q
A
A
S
W
G
G
L
D
L
P
N
N
Rhesus Macaque
Macaca mulatta
O77680
446
49274
S172
K
A
K
P
T
S
P
S
D
G
N
A
T
S
L
Dog
Lupus familis
XP_546227
446
49338
S172
K
A
K
P
T
S
S
S
D
G
N
A
T
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61616
446
49594
L171
K
A
K
P
T
W
P
L
D
G
N
F
T
S
L
Rat
Rattus norvegicus
P18901
446
49410
L171
K
A
K
P
T
W
P
L
D
G
N
F
T
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521446
353
37571
A104
W
H
K
A
P
A
D
A
T
G
R
P
A
S
T
Chicken
Gallus gallus
NP_001138320
451
50438
L171
K
A
T
T
T
S
F
L
D
L
N
A
S
L
Q
Frog
Xenopus laevis
P42289
451
50531
F171
K
A
K
T
T
S
F
F
D
L
N
I
T
L
H
Zebra Danio
Brachydanio rerio
NP_001129448
446
49800
T170
K
A
Q
T
T
S
Y
T
E
L
N
G
T
Y
G
Tiger Blowfish
Takifugu rubipres
P53452
459
51062
V172
K
A
Q
T
A
S
Y
V
E
L
N
G
T
Y
A
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011595
402
44536
A153
I
A
V
V
W
L
L
A
G
L
I
S
F
V
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198071
459
51464
S199
T
V
P
G
S
Q
N
S
L
E
M
D
P
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.1
99.7
95.5
N.A.
91.2
90.3
N.A.
42.8
81.3
80.2
72.8
70.1
N.A.
35.4
N.A.
42.2
Protein Similarity:
100
70
99.7
97.7
N.A.
94.1
93.5
N.A.
56
88.4
86.6
83.1
79.7
N.A.
51.5
N.A.
56.4
P-Site Identity:
100
6.6
100
93.3
N.A.
80
80
N.A.
20
46.6
53.3
40
33.3
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
33.3
100
93.3
N.A.
80
80
N.A.
33.3
53.3
53.3
60
46.6
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
77
0
16
16
8
0
16
0
0
0
31
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
8
0
54
0
8
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
16
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
16
8
0
0
0
16
8
0
0
% F
% Gly:
0
0
0
8
0
0
0
8
16
47
0
16
0
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% I
% Lys:
70
0
54
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
8
24
8
47
0
8
0
16
39
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
70
0
0
8
8
% N
% Pro:
0
0
8
39
8
0
31
0
0
0
0
8
16
8
8
% P
% Gln:
0
0
24
0
0
8
0
0
0
0
0
0
0
0
16
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
8
62
8
31
0
0
0
8
8
47
0
% S
% Thr:
8
0
8
31
62
0
0
8
8
0
0
0
62
0
8
% T
% Val:
0
8
8
8
0
0
0
8
0
0
0
0
0
8
0
% V
% Trp:
8
0
0
0
8
16
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
16
0
0
0
0
0
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _