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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD1
All Species:
13.64
Human Site:
S254
Identified Species:
25
UniProt:
P21728
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21728
NP_000785.1
446
49293
S254
N
G
K
P
V
E
C
S
Q
P
E
S
S
F
K
Chimpanzee
Pan troglodytes
XP_528711
477
53003
C278
S
C
R
S
S
A
A
C
A
P
D
T
S
L
R
Rhesus Macaque
Macaca mulatta
O77680
446
49274
S254
N
G
K
P
V
E
C
S
Q
P
E
S
S
F
K
Dog
Lupus familis
XP_546227
446
49338
S254
N
G
N
P
V
E
C
S
Q
P
E
S
S
F
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61616
446
49594
S254
N
G
N
P
V
E
C
S
Q
S
E
S
S
F
K
Rat
Rattus norvegicus
P18901
446
49410
A254
N
G
N
P
V
E
C
A
Q
S
E
S
S
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521446
353
37571
R176
R
G
A
G
P
P
D
R
P
A
R
S
G
P
R
Chicken
Gallus gallus
NP_001138320
451
50438
Q253
N
R
S
S
M
D
C
Q
Q
P
E
S
N
F
K
Frog
Xenopus laevis
P42289
451
50531
Q253
N
R
N
S
L
D
C
Q
Q
P
E
S
S
L
K
Zebra Danio
Brachydanio rerio
NP_001129448
446
49800
M249
S
M
G
N
N
A
S
M
E
S
E
S
S
F
K
Tiger Blowfish
Takifugu rubipres
P53452
459
51062
M252
S
M
G
N
S
L
S
M
E
S
E
C
S
F
K
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011595
402
44536
S225
Y
A
Q
K
H
V
K
S
I
R
A
V
T
K
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198071
459
51464
L274
A
K
T
L
G
T
I
L
G
V
F
I
C
C
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.1
99.7
95.5
N.A.
91.2
90.3
N.A.
42.8
81.3
80.2
72.8
70.1
N.A.
35.4
N.A.
42.2
Protein Similarity:
100
70
99.7
97.7
N.A.
94.1
93.5
N.A.
56
88.4
86.6
83.1
79.7
N.A.
51.5
N.A.
56.4
P-Site Identity:
100
13.3
100
93.3
N.A.
86.6
80
N.A.
13.3
53.3
53.3
33.3
26.6
N.A.
6.6
N.A.
0
P-Site Similarity:
100
46.6
100
93.3
N.A.
86.6
86.6
N.A.
20
73.3
66.6
46.6
40
N.A.
20
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
16
8
8
8
8
8
0
0
0
0
% A
% Cys:
0
8
0
0
0
0
54
8
0
0
0
8
8
8
0
% C
% Asp:
0
0
0
0
0
16
8
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
39
0
0
16
0
70
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
62
0
% F
% Gly:
0
47
16
8
8
0
0
0
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
8
0
0
8
0
0
0
% I
% Lys:
0
8
16
8
0
0
8
0
0
0
0
0
0
8
70
% K
% Leu:
0
0
0
8
8
8
0
8
0
0
0
0
0
16
8
% L
% Met:
0
16
0
0
8
0
0
16
0
0
0
0
0
0
0
% M
% Asn:
54
0
31
16
8
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
39
8
8
0
0
8
47
0
0
0
8
0
% P
% Gln:
0
0
8
0
0
0
0
16
54
0
0
0
0
0
0
% Q
% Arg:
8
16
8
0
0
0
0
8
0
8
8
0
0
0
16
% R
% Ser:
24
0
8
24
16
0
16
39
0
31
0
70
70
0
0
% S
% Thr:
0
0
8
0
0
8
0
0
0
0
0
8
8
0
0
% T
% Val:
0
0
0
0
39
8
0
0
0
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _