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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD1
All Species:
30.61
Human Site:
S259
Identified Species:
56.11
UniProt:
P21728
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21728
NP_000785.1
446
49293
S259
E
C
S
Q
P
E
S
S
F
K
M
S
F
K
R
Chimpanzee
Pan troglodytes
XP_528711
477
53003
S283
A
A
C
A
P
D
T
S
L
R
A
S
I
K
K
Rhesus Macaque
Macaca mulatta
O77680
446
49274
S259
E
C
S
Q
P
E
S
S
F
K
M
S
F
K
R
Dog
Lupus familis
XP_546227
446
49338
S259
E
C
S
Q
P
E
S
S
F
K
M
S
F
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61616
446
49594
S259
E
C
S
Q
S
E
S
S
F
K
M
S
F
K
R
Rat
Rattus norvegicus
P18901
446
49410
S259
E
C
A
Q
S
E
S
S
F
K
M
S
F
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521446
353
37571
G181
P
D
R
P
A
R
S
G
P
R
A
S
V
R
R
Chicken
Gallus gallus
NP_001138320
451
50438
N258
D
C
Q
Q
P
E
S
N
F
K
M
S
F
K
R
Frog
Xenopus laevis
P42289
451
50531
S258
D
C
Q
Q
P
E
S
S
L
K
T
S
F
K
R
Zebra Danio
Brachydanio rerio
NP_001129448
446
49800
S254
A
S
M
E
S
E
S
S
F
K
M
S
F
K
R
Tiger Blowfish
Takifugu rubipres
P53452
459
51062
S257
L
S
M
E
S
E
C
S
F
K
M
S
F
K
R
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011595
402
44536
T230
V
K
S
I
R
A
V
T
K
L
P
D
T
S
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198071
459
51464
C279
T
I
L
G
V
F
I
C
C
W
L
P
F
F
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.1
99.7
95.5
N.A.
91.2
90.3
N.A.
42.8
81.3
80.2
72.8
70.1
N.A.
35.4
N.A.
42.2
Protein Similarity:
100
70
99.7
97.7
N.A.
94.1
93.5
N.A.
56
88.4
86.6
83.1
79.7
N.A.
51.5
N.A.
56.4
P-Site Identity:
100
26.6
100
100
N.A.
93.3
86.6
N.A.
20
80
73.3
66.6
60
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
53.3
100
100
N.A.
93.3
93.3
N.A.
33.3
93.3
80
73.3
66.6
N.A.
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
8
8
8
8
0
0
0
0
16
0
0
0
0
% A
% Cys:
0
54
8
0
0
0
8
8
8
0
0
0
0
0
0
% C
% Asp:
16
8
0
0
0
8
0
0
0
0
0
8
0
0
0
% D
% Glu:
39
0
0
16
0
70
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
62
0
0
0
77
8
0
% F
% Gly:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
0
0
8
0
0
0
0
0
8
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
8
70
0
0
0
77
8
% K
% Leu:
8
0
8
0
0
0
0
0
16
8
8
0
0
0
0
% L
% Met:
0
0
16
0
0
0
0
0
0
0
62
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
8
47
0
0
0
8
0
8
8
0
0
0
% P
% Gln:
0
0
16
54
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
8
8
0
0
0
16
0
0
0
8
77
% R
% Ser:
0
16
39
0
31
0
70
70
0
0
0
85
0
8
0
% S
% Thr:
8
0
0
0
0
0
8
8
0
0
8
0
8
0
0
% T
% Val:
8
0
0
0
8
0
8
0
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _