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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD1
All Species:
17.88
Human Site:
T182
Identified Species:
32.78
UniProt:
P21728
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21728
NP_000785.1
446
49293
T182
N
A
T
S
L
A
E
T
I
D
N
C
D
S
S
Chimpanzee
Pan troglodytes
XP_528711
477
53003
N199
D
L
P
N
N
L
A
N
W
T
P
W
E
E
D
Rhesus Macaque
Macaca mulatta
O77680
446
49274
T182
N
A
T
S
L
A
E
T
I
D
N
C
D
S
S
Dog
Lupus familis
XP_546227
446
49338
T182
N
A
T
S
L
G
E
T
M
D
N
C
D
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61616
446
49594
A181
N
F
T
S
L
E
D
A
E
D
D
N
C
D
T
Rat
Rattus norvegicus
P18901
446
49410
T181
N
F
T
S
L
E
D
T
E
D
D
N
C
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521446
353
37571
D114
R
P
A
S
T
G
C
D
S
S
L
N
R
A
Y
Chicken
Gallus gallus
NP_001138320
451
50438
S181
N
A
S
L
Q
G
I
S
M
D
N
C
D
S
S
Frog
Xenopus laevis
P42289
451
50531
T181
N
I
T
L
H
D
R
T
M
D
N
C
D
S
S
Zebra Danio
Brachydanio rerio
NP_001129448
446
49800
P180
N
G
T
Y
G
E
L
P
P
D
N
C
D
S
S
Tiger Blowfish
Takifugu rubipres
P53452
459
51062
L182
N
G
T
Y
A
G
D
L
P
P
D
N
C
D
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011595
402
44536
L163
I
S
F
V
P
I
S
L
G
L
H
R
A
N
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198071
459
51464
F209
M
D
P
P
Q
C
V
F
L
L
N
P
Y
Y
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.1
99.7
95.5
N.A.
91.2
90.3
N.A.
42.8
81.3
80.2
72.8
70.1
N.A.
35.4
N.A.
42.2
Protein Similarity:
100
70
99.7
97.7
N.A.
94.1
93.5
N.A.
56
88.4
86.6
83.1
79.7
N.A.
51.5
N.A.
56.4
P-Site Identity:
100
0
100
86.6
N.A.
33.3
40
N.A.
6.6
53.3
60
53.3
20
N.A.
0
N.A.
6.6
P-Site Similarity:
100
20
100
93.3
N.A.
53.3
60
N.A.
13.3
73.3
66.6
53.3
33.3
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
8
0
8
16
8
8
0
0
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
8
8
0
0
0
0
47
24
0
0
% C
% Asp:
8
8
0
0
0
8
24
8
0
62
24
0
47
24
8
% D
% Glu:
0
0
0
0
0
24
24
0
16
0
0
0
8
8
8
% E
% Phe:
0
16
8
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
16
0
0
8
31
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
8
0
0
0
8
8
0
16
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
16
39
8
8
16
8
16
8
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% M
% Asn:
70
0
0
8
8
0
0
8
0
0
54
31
0
8
0
% N
% Pro:
0
8
16
8
8
0
0
8
16
8
8
8
0
0
0
% P
% Gln:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
8
0
0
0
0
8
8
0
0
% R
% Ser:
0
8
8
47
0
0
8
8
8
8
0
0
0
47
54
% S
% Thr:
0
0
62
0
8
0
0
39
0
8
0
0
0
0
16
% T
% Val:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% W
% Tyr:
0
0
0
16
0
0
0
0
0
0
0
0
8
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _