KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD1
All Species:
43.94
Human Site:
T268
Identified Species:
80.56
UniProt:
P21728
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21728
NP_000785.1
446
49293
T268
K
M
S
F
K
R
E
T
K
V
L
K
T
L
S
Chimpanzee
Pan troglodytes
XP_528711
477
53003
T292
R
A
S
I
K
K
E
T
K
V
L
K
T
L
S
Rhesus Macaque
Macaca mulatta
O77680
446
49274
T268
K
M
S
F
K
R
E
T
K
V
L
K
T
L
S
Dog
Lupus familis
XP_546227
446
49338
T268
K
M
S
F
K
R
E
T
K
V
L
K
T
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61616
446
49594
T268
K
M
S
F
K
R
E
T
K
V
L
K
T
L
S
Rat
Rattus norvegicus
P18901
446
49410
T268
K
M
S
F
K
R
E
T
K
V
L
K
T
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521446
353
37571
T190
R
A
S
V
R
R
E
T
E
V
L
K
T
L
A
Chicken
Gallus gallus
NP_001138320
451
50438
T267
K
M
S
F
K
R
E
T
K
V
L
K
T
L
S
Frog
Xenopus laevis
P42289
451
50531
T267
K
T
S
F
K
R
E
T
K
V
L
K
T
L
S
Zebra Danio
Brachydanio rerio
NP_001129448
446
49800
T263
K
M
S
F
K
R
E
T
K
V
L
K
T
L
S
Tiger Blowfish
Takifugu rubipres
P53452
459
51062
T266
K
M
S
F
K
R
E
T
K
V
L
K
T
L
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011595
402
44536
K239
L
P
D
T
S
M
A
K
S
F
V
R
K
V
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198071
459
51464
N288
W
L
P
F
F
V
V
N
C
I
L
P
F
C
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.1
99.7
95.5
N.A.
91.2
90.3
N.A.
42.8
81.3
80.2
72.8
70.1
N.A.
35.4
N.A.
42.2
Protein Similarity:
100
70
99.7
97.7
N.A.
94.1
93.5
N.A.
56
88.4
86.6
83.1
79.7
N.A.
51.5
N.A.
56.4
P-Site Identity:
100
73.3
100
100
N.A.
100
100
N.A.
60
100
93.3
100
100
N.A.
0
N.A.
13.3
P-Site Similarity:
100
86.6
100
100
N.A.
100
100
N.A.
86.6
100
93.3
100
100
N.A.
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
0
8
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
85
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
77
8
0
0
0
0
8
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
70
0
0
0
77
8
0
8
77
0
0
85
8
0
0
% K
% Leu:
8
8
0
0
0
0
0
0
0
0
93
0
0
85
0
% L
% Met:
0
62
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
8
8
0
0
0
0
0
0
0
0
8
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
16
0
0
0
8
77
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
85
0
8
0
0
0
8
0
0
0
0
0
77
% S
% Thr:
0
8
0
8
0
0
0
85
0
0
0
0
85
0
0
% T
% Val:
0
0
0
8
0
8
8
0
0
85
8
0
0
8
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _