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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD1
All Species:
29.49
Human Site:
T446
Identified Species:
54.07
UniProt:
P21728
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21728
NP_000785.1
446
49293
T446
T
Q
N
G
Q
H
P
T
_
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_528711
477
53003
P473
D
K
I
T
P
F
T
P
N
G
F
H
_
_
_
Rhesus Macaque
Macaca mulatta
O77680
446
49274
T446
T
Q
N
G
Q
H
P
T
_
_
_
_
_
_
_
Dog
Lupus familis
XP_546227
446
49338
T446
T
Q
N
G
Q
H
P
T
_
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q61616
446
49594
T446
T
H
S
G
Q
H
S
T
_
_
_
_
_
_
_
Rat
Rattus norvegicus
P18901
446
49410
T446
T
H
S
G
Q
H
S
T
_
_
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521446
353
37571
Chicken
Gallus gallus
NP_001138320
451
50438
T451
T
Q
N
G
Q
H
K
T
_
_
_
_
_
_
_
Frog
Xenopus laevis
P42289
451
50531
T451
T
Q
N
G
Q
P
K
T
_
_
_
_
_
_
_
Zebra Danio
Brachydanio rerio
NP_001129448
446
49800
S443
T
Q
N
G
Q
H
K
S
I
P
C
_
_
_
_
Tiger Blowfish
Takifugu rubipres
P53452
459
51062
S456
T
Q
N
G
Q
H
K
S
M
S
C
_
_
_
_
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011595
402
44536
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198071
459
51464
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.1
99.7
95.5
N.A.
91.2
90.3
N.A.
42.8
81.3
80.2
72.8
70.1
N.A.
35.4
N.A.
42.2
Protein Similarity:
100
70
99.7
97.7
N.A.
94.1
93.5
N.A.
56
88.4
86.6
83.1
79.7
N.A.
51.5
N.A.
56.4
P-Site Identity:
100
0
100
100
N.A.
62.5
62.5
N.A.
0
87.5
75
54.5
54.5
N.A.
0
N.A.
0
P-Site Similarity:
100
16.6
100
100
N.A.
75
75
N.A.
0
87.5
75
72.7
63.6
N.A.
0
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
70
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
16
0
0
0
62
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
31
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
54
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
8
24
8
0
8
0
0
0
0
0
% P
% Gln:
0
54
0
0
70
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
16
0
0
0
16
16
0
8
0
0
0
0
0
% S
% Thr:
70
0
0
8
0
0
8
54
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
54
54
54
70
77
77
77
% _