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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MDK
All Species:
27.88
Human Site:
T65
Identified Species:
68.15
UniProt:
P21741
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21741
NP_001012333.1
143
15585
T65
E
G
T
C
G
A
Q
T
Q
R
I
R
C
R
V
Chimpanzee
Pan troglodytes
XP_001149958
225
24069
T147
R
H
W
A
T
A
P
T
Q
R
I
R
C
R
V
Rhesus Macaque
Macaca mulatta
XP_001112400
166
17706
T65
E
G
T
C
G
A
Q
T
Q
R
I
R
C
R
V
Dog
Lupus familis
XP_851259
143
15443
D65
R
G
Y
P
R
G
P
D
P
A
H
P
V
P
G
Cat
Felis silvestris
Mouse
Mus musculus
P12025
140
15415
T62
E
G
T
C
G
A
Q
T
Q
R
V
H
C
K
V
Rat
Rattus norvegicus
Q9R1S9
140
15387
T62
E
G
T
C
G
A
Q
T
Q
R
I
H
C
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513099
228
25087
E90
E
G
T
R
A
G
A
E
C
K
Q
T
M
K
T
Chicken
Gallus gallus
P24052
142
15561
S64
E
G
S
C
G
D
E
S
R
K
L
K
C
K
I
Frog
Xenopus laevis
P48531
142
15577
T64
E
G
T
C
K
E
E
T
R
K
L
K
C
K
I
Zebra Danio
Brachydanio rerio
NP_571145
146
15762
T67
E
G
T
C
N
E
Q
T
R
K
V
K
C
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.7
83.1
66.4
N.A.
86
86.7
N.A.
32.4
64.3
60.8
58.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
50.6
84.9
69.2
N.A.
91.6
92.3
N.A.
45.1
79.7
78.3
72.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
60
100
6.6
N.A.
80
86.6
N.A.
20
33.3
40
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
100
6.6
N.A.
93.3
93.3
N.A.
33.3
93.3
86.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
50
10
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
70
0
0
0
0
10
0
0
0
80
0
0
% C
% Asp:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% D
% Glu:
80
0
0
0
0
20
20
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
90
0
0
50
20
0
0
0
0
0
0
0
0
10
% G
% His:
0
10
0
0
0
0
0
0
0
0
10
20
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
40
0
0
0
20
% I
% Lys:
0
0
0
0
10
0
0
0
0
40
0
30
0
50
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
20
0
10
0
0
10
0
10
0
% P
% Gln:
0
0
0
0
0
0
50
0
50
0
10
0
0
0
0
% Q
% Arg:
20
0
0
10
10
0
0
0
30
50
0
30
0
40
0
% R
% Ser:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% S
% Thr:
0
0
70
0
10
0
0
70
0
0
0
10
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
20
0
10
0
60
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _