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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZP3
All Species:
10.74
Human Site:
S421
Identified Species:
29.55
UniProt:
P21754
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21754
NP_001103824.1
424
47018
S421
R
T
A
S
H
P
V
S
A
S
E
_
_
_
_
Chimpanzee
Pan troglodytes
XP_528035
277
30823
Rhesus Macaque
Macaca mulatta
XP_001114760
793
84525
S790
R
T
A
S
R
S
V
S
V
S
Q
_
_
_
_
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P10761
424
46285
S421
H
S
S
S
Y
L
V
S
L
P
Q
_
_
_
_
Rat
Rattus norvegicus
P97708
424
45882
S421
H
T
S
S
Y
L
V
S
L
P
Q
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512792
477
51439
Chicken
Gallus gallus
XP_413701
437
47528
R421
L
W
S
S
S
G
R
R
V
P
A
G
K
A
P
Frog
Xenopus laevis
NP_001081657
460
50066
T457
K
R
K
Q
Y
I
S
T
I
Q
K
_
_
_
_
Zebra Danio
Brachydanio rerio
NP_001025291
432
47510
K428
P
S
Q
S
S
G
I
K
V
V
S
F
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.3
49.1
N.A.
N.A.
67.4
66.2
N.A.
39.6
44.6
39.5
35.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
64.6
51.4
N.A.
N.A.
77.8
77.3
N.A.
54.7
61
58.9
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
63.6
N.A.
N.A.
27.2
36.3
N.A.
0
6.6
0
8.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
72.7
N.A.
N.A.
63.6
63.6
N.A.
0
20
36.3
25
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
23
0
0
0
0
0
12
0
12
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
0
23
0
0
0
0
0
12
0
0
0
% G
% His:
23
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
12
12
0
12
0
0
0
0
0
0
% I
% Lys:
12
0
12
0
0
0
0
12
0
0
12
0
12
0
0
% K
% Leu:
12
0
0
0
0
23
0
0
23
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
0
0
0
12
0
0
0
34
0
0
0
0
12
% P
% Gln:
0
0
12
12
0
0
0
0
0
12
34
0
0
0
0
% Q
% Arg:
23
12
0
0
12
0
12
12
0
0
0
0
0
0
0
% R
% Ser:
0
23
34
67
23
12
12
45
0
23
12
0
0
0
0
% S
% Thr:
0
34
0
0
0
0
0
12
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
45
0
34
12
0
0
0
0
0
% V
% Trp:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
56
67
67
67
% _