KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR2
All Species:
33.94
Human Site:
Y733
Identified Species:
74.67
UniProt:
P21802
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21802
NP_000132.3
821
92025
Y733
A
N
C
T
N
E
L
Y
M
M
M
R
D
C
W
Chimpanzee
Pan troglodytes
XP_521622
819
91776
Y731
A
N
C
T
N
E
L
Y
M
M
M
R
D
C
W
Rhesus Macaque
Macaca mulatta
XP_001106418
825
91775
Y737
A
N
C
T
N
E
L
Y
M
M
M
R
D
C
W
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P21803
821
91965
Y733
T
N
C
T
N
E
L
Y
M
M
M
R
D
C
W
Rat
Rattus norvegicus
Q04589
822
91806
Y730
S
N
C
T
N
E
L
Y
M
M
M
R
D
C
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P18461
823
92281
Y735
A
N
C
T
N
E
L
Y
M
M
M
R
D
C
W
Frog
Xenopus laevis
Q03364
813
91322
Y723
A
N
C
T
N
E
L
Y
M
M
M
R
D
C
W
Zebra Danio
Brachydanio rerio
Q8JG38
817
91370
Y729
A
N
C
T
N
E
L
Y
M
M
M
K
D
C
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09147
1052
117795
A965
G
Q
R
M
E
K
P
A
K
C
S
L
N
I
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10656
1040
118938
Y904
H
L
C
P
Q
E
V
Y
H
L
M
C
S
C
W
Sea Urchin
Strong. purpuratus
Q26614
972
110463
E878
L
R
S
G
K
R
L
E
K
P
Q
N
T
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
88.3
N.A.
N.A.
96.9
71.7
N.A.
N.A.
92.8
77.5
77.4
N.A.
29
N.A.
31.6
34.4
Protein Similarity:
100
99.6
90.9
N.A.
N.A.
98.1
83.8
N.A.
N.A.
96.3
87.2
86.5
N.A.
45.1
N.A.
46.5
51.7
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
N.A.
100
100
93.3
N.A.
0
N.A.
40
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
100
N.A.
N.A.
100
100
100
N.A.
20
N.A.
53.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
55
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
82
0
0
0
0
0
0
10
0
10
0
82
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
73
0
0
% D
% Glu:
0
0
0
0
10
82
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
10
10
0
0
19
0
0
10
0
0
0
% K
% Leu:
10
10
0
0
0
0
82
0
0
10
0
10
0
0
10
% L
% Met:
0
0
0
10
0
0
0
0
73
73
82
0
0
0
0
% M
% Asn:
0
73
0
0
73
0
0
0
0
0
0
10
10
0
0
% N
% Pro:
0
0
0
10
0
0
10
0
0
10
0
0
0
0
0
% P
% Gln:
0
10
0
0
10
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
10
10
0
0
10
0
0
0
0
0
64
0
0
0
% R
% Ser:
10
0
10
0
0
0
0
0
0
0
10
0
10
10
0
% S
% Thr:
10
0
0
73
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
82
% W
% Tyr:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _