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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD4
All Species:
33.94
Human Site:
Y143
Identified Species:
67.88
UniProt:
P21917
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21917
NP_000788.2
467
48361
Y143
A
V
A
V
P
L
R
Y
N
R
Q
G
G
S
R
Chimpanzee
Pan troglodytes
Q5IS72
400
44218
Y138
A
V
V
M
P
V
H
Y
Q
H
G
T
G
Q
S
Rhesus Macaque
Macaca mulatta
XP_001087197
428
45026
Y139
A
V
A
V
P
L
R
Y
N
R
Q
G
G
S
H
Dog
Lupus familis
XP_848930
386
41168
Y198
A
V
A
V
P
L
S
Y
N
R
Q
G
G
G
G
Cat
Felis silvestris
Mouse
Mus musculus
P51436
387
41468
Y140
A
V
T
V
P
L
R
Y
N
Q
Q
G
Q
C
Q
Rat
Rattus norvegicus
P30729
387
41276
Y140
A
V
T
V
P
L
R
Y
N
Q
Q
G
Q
C
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001106761
437
49525
Y139
A
V
A
M
P
M
L
Y
N
T
R
Y
S
S
K
Frog
Xenopus laevis
P24628
442
49720
Y136
A
V
A
M
P
M
L
Y
N
T
R
Y
S
S
K
Zebra Danio
Brachydanio rerio
Q90WY6
432
49119
Y143
S
V
T
Q
A
V
E
Y
N
L
K
R
T
P
R
Tiger Blowfish
Takifugu rubipres
P53453
463
52101
Y140
A
V
A
M
P
M
L
Y
N
T
R
Y
S
S
R
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
Y184
A
V
T
Q
P
I
K
Y
A
K
H
K
N
S
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
Y151
A
G
Q
D
P
I
G
Y
R
D
K
V
S
K
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.1
88
29.1
N.A.
67.4
66.5
N.A.
N.A.
33.6
33.4
30.1
35.5
32
N.A.
25.5
N.A.
Protein Similarity:
100
49.2
88.8
37
N.A.
70.8
70.4
N.A.
N.A.
49.8
48.8
47.1
50.5
47
N.A.
39.4
N.A.
P-Site Identity:
100
33.3
93.3
80
N.A.
66.6
66.6
N.A.
N.A.
46.6
46.6
26.6
53.3
40
N.A.
26.6
N.A.
P-Site Similarity:
100
46.6
93.3
80
N.A.
80
80
N.A.
N.A.
73.3
73.3
46.6
73.3
60
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
92
0
50
0
9
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
9
0
0
0
9
42
34
9
9
% G
% His:
0
0
0
0
0
0
9
0
0
9
9
0
0
0
9
% H
% Ile:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
9
17
9
0
9
17
% K
% Leu:
0
0
0
0
0
42
25
0
0
9
0
0
0
0
0
% L
% Met:
0
0
0
34
0
25
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
75
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
92
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
9
17
0
0
0
0
9
17
42
0
17
9
17
% Q
% Arg:
0
0
0
0
0
0
34
0
9
25
25
9
0
0
42
% R
% Ser:
9
0
0
0
0
0
9
0
0
0
0
0
34
50
9
% S
% Thr:
0
0
34
0
0
0
0
0
0
25
0
9
9
0
0
% T
% Val:
0
92
9
42
0
17
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _