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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD4
All Species:
17.88
Human Site:
Y192
Identified Species:
35.76
UniProt:
P21917
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21917
NP_000788.2
467
48361
Y192
C
R
L
E
D
R
D
Y
V
V
Y
S
S
V
C
Chimpanzee
Pan troglodytes
Q5IS72
400
44218
F188
C
S
I
S
N
P
D
F
V
I
Y
S
S
V
V
Rhesus Macaque
Macaca mulatta
XP_001087197
428
45026
Y188
C
R
L
E
D
R
D
Y
V
V
Y
S
S
V
C
Dog
Lupus familis
XP_848930
386
41168
R233
L
C
G
L
N
D
A
R
G
R
D
P
A
V
C
Cat
Felis silvestris
Mouse
Mus musculus
P51436
387
41468
Y187
C
C
L
E
N
R
D
Y
V
V
Y
S
S
V
C
Rat
Rattus norvegicus
P30729
387
41276
Y187
C
C
L
E
D
R
D
Y
V
V
Y
S
S
I
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001106761
437
49525
F186
C
I
I
A
N
P
A
F
V
V
Y
S
S
V
V
Frog
Xenopus laevis
P24628
442
49720
F183
C
I
I
D
N
P
A
F
V
I
Y
S
S
I
V
Zebra Danio
Brachydanio rerio
Q90WY6
432
49119
Y194
Q
L
N
D
H
T
W
Y
I
L
Y
S
S
I
G
Tiger Blowfish
Takifugu rubipres
P53453
463
52101
F190
C
F
I
A
N
P
A
F
V
V
Y
S
S
I
V
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
F233
C
A
F
Y
N
A
D
F
I
L
Y
S
S
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
Y204
L
F
T
D
S
K
M
Y
V
S
F
S
S
L
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.1
88
29.1
N.A.
67.4
66.5
N.A.
N.A.
33.6
33.4
30.1
35.5
32
N.A.
25.5
N.A.
Protein Similarity:
100
49.2
88.8
37
N.A.
70.8
70.4
N.A.
N.A.
49.8
48.8
47.1
50.5
47
N.A.
39.4
N.A.
P-Site Identity:
100
46.6
100
13.3
N.A.
86.6
86.6
N.A.
N.A.
46.6
33.3
26.6
40
33.3
N.A.
26.6
N.A.
P-Site Similarity:
100
73.3
100
26.6
N.A.
93.3
93.3
N.A.
N.A.
66.6
73.3
53.3
66.6
66.6
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
17
0
9
34
0
0
0
0
0
9
0
0
% A
% Cys:
75
25
0
0
0
0
0
0
0
0
0
0
0
0
42
% C
% Asp:
0
0
0
25
25
9
50
0
0
0
9
0
0
0
0
% D
% Glu:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
17
9
0
0
0
0
42
0
0
9
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
9
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
17
34
0
0
0
0
0
17
17
0
0
0
34
0
% I
% Lys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
17
9
34
9
0
0
0
0
0
17
0
0
0
17
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
59
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
34
0
0
0
0
0
9
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
17
0
0
0
34
0
9
0
9
0
0
0
0
0
% R
% Ser:
0
9
0
9
9
0
0
0
0
9
0
92
92
0
9
% S
% Thr:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
75
50
0
0
0
50
42
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
50
0
0
84
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _