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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DRD5 All Species: 11.21
Human Site: T282 Identified Species: 22.42
UniProt: P21918 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P21918 NP_000789.1 477 52951 T282 S A A C A P D T S L R A S I K
Chimpanzee Pan troglodytes XP_528711 477 53003 T282 S A A C A P D T S L R A S I K
Rhesus Macaque Macaca mulatta O77680 446 49274 V270 S F K R E T K V L K T L S V I
Dog Lupus familis XP_545942 645 69818 T451 R A A C A P D T S L R A S I K
Cat Felis silvestris
Mouse Mus musculus Q8BLD9 478 53058 P276 R G A C E P D P S L R A S I K
Rat Rattus norvegicus P25115 475 52812 P276 R G A Y E P D P S L R A S I K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521446 353 37571 P177 G A G P P D R P A R S G P R A
Chicken Gallus gallus XP_426351 648 69599 H461 N H V D C H H H T S L K S S I
Frog Xenopus laevis P42290 457 51638 S273 H Q T S L R T S I K K E T K V
Zebra Danio Brachydanio rerio XP_692025 474 53236 N287 S N D C S N E N S L K T T F K
Tiger Blowfish Takifugu rubipres P53454 463 51077 V278 K V L K T L S V I M G V F V F
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198071 459 51464 T272 K A A K T L G T I L G V F I C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 55.1 63.2 N.A. 82.8 82.3 N.A. 43.4 55.2 66.4 54.5 54.9 N.A. N.A. N.A. 36.2
Protein Similarity: 100 98.9 70.4 66.8 N.A. 88.9 87.8 N.A. 53.6 62.3 76.7 66.2 68.3 N.A. N.A. N.A. 51.3
P-Site Identity: 100 100 13.3 93.3 N.A. 73.3 66.6 N.A. 6.6 6.6 0 33.3 0 N.A. N.A. N.A. 33.3
P-Site Similarity: 100 100 20 93.3 N.A. 73.3 66.6 N.A. 13.3 20 20 60 13.3 N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 42 50 0 25 0 0 0 9 0 0 42 0 0 9 % A
% Cys: 0 0 0 42 9 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 9 9 0 9 42 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 25 0 9 0 0 0 0 9 0 0 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 17 9 9 % F
% Gly: 9 17 9 0 0 0 9 0 0 0 17 9 0 0 0 % G
% His: 9 9 0 0 0 9 9 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 25 0 0 0 0 50 17 % I
% Lys: 17 0 9 17 0 0 9 0 0 17 17 9 0 9 50 % K
% Leu: 0 0 9 0 9 17 0 0 9 59 9 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 9 9 0 0 0 9 0 9 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 9 9 42 0 25 0 0 0 0 9 0 0 % P
% Gln: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 25 0 0 9 0 9 9 0 0 9 42 0 0 9 0 % R
% Ser: 34 0 0 9 9 0 9 9 50 9 9 0 59 9 0 % S
% Thr: 0 0 9 0 17 9 9 34 9 0 9 9 17 0 0 % T
% Val: 0 9 9 0 0 0 0 17 0 0 0 17 0 17 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _