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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD5
All Species:
18.79
Human Site:
T419
Identified Species:
37.58
UniProt:
P21918
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21918
NP_000789.1
477
52951
T419
H
M
M
P
N
A
V
T
P
G
N
R
E
V
D
Chimpanzee
Pan troglodytes
XP_528711
477
53003
T419
H
M
M
P
N
A
V
T
P
G
N
R
E
V
D
Rhesus Macaque
Macaca mulatta
O77680
446
49274
G396
Y
L
I
P
H
A
V
G
S
S
E
D
L
K
K
Dog
Lupus familis
XP_545942
645
69818
T588
H
M
I
P
N
A
V
T
P
G
D
G
E
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLD9
478
53058
S414
H
M
I
P
N
A
V
S
S
G
D
R
E
V
G
Rat
Rattus norvegicus
P25115
475
52812
S414
H
M
I
P
N
A
V
S
S
G
D
R
E
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521446
353
37571
Y303
P
G
R
A
V
A
A
Y
G
D
V
L
P
D
E
Chicken
Gallus gallus
XP_426351
648
69599
V597
Y
V
N
M
I
P
N
V
V
D
C
E
E
N
R
Frog
Xenopus laevis
P42290
457
51638
D405
N
M
I
P
N
V
V
D
C
I
D
D
N
E
D
Zebra Danio
Brachydanio rerio
XP_692025
474
53236
E413
Q
M
A
N
T
R
E
E
Q
S
L
P
F
D
K
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
S409
G
P
N
F
D
K
V
S
V
V
S
D
D
S
R
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198071
459
51464
A402
P
A
E
G
S
G
S
A
S
P
S
N
P
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
55.1
63.2
N.A.
82.8
82.3
N.A.
43.4
55.2
66.4
54.5
54.9
N.A.
N.A.
N.A.
36.2
Protein Similarity:
100
98.9
70.4
66.8
N.A.
88.9
87.8
N.A.
53.6
62.3
76.7
66.2
68.3
N.A.
N.A.
N.A.
51.3
P-Site Identity:
100
100
20
80
N.A.
66.6
66.6
N.A.
6.6
6.6
33.3
6.6
6.6
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
46.6
93.3
N.A.
86.6
86.6
N.A.
13.3
20
53.3
6.6
33.3
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
9
0
59
9
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
9
0
17
34
25
9
17
34
% D
% Glu:
0
0
9
0
0
0
9
9
0
0
9
9
50
9
9
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
9
9
0
9
0
9
0
9
9
42
0
9
0
9
17
% G
% His:
42
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
42
0
9
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
17
% K
% Leu:
0
9
0
0
0
0
0
0
0
0
9
9
9
0
0
% L
% Met:
0
59
17
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
17
9
50
0
9
0
0
0
17
9
9
9
0
% N
% Pro:
17
9
0
59
0
9
0
0
25
9
0
9
17
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
9
0
0
0
0
0
34
0
0
17
% R
% Ser:
0
0
0
0
9
0
9
25
34
17
17
0
0
9
0
% S
% Thr:
0
0
0
0
9
0
0
25
0
0
0
0
0
0
9
% T
% Val:
0
9
0
0
9
9
67
9
17
9
9
0
0
42
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _