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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD5
All Species:
16.67
Human Site:
Y148
Identified Species:
33.33
UniProt:
P21918
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21918
NP_000789.1
477
52951
Y148
A
I
S
R
P
F
R
Y
K
R
K
M
T
Q
R
Chimpanzee
Pan troglodytes
XP_528711
477
53003
Y148
A
I
S
R
P
F
R
Y
V
R
K
M
T
Q
R
Rhesus Macaque
Macaca mulatta
O77680
446
49274
A139
E
R
K
M
T
P
K
A
A
F
I
L
I
S
V
Dog
Lupus familis
XP_545942
645
69818
Y318
I
L
N
L
P
F
R
Y
E
R
K
M
T
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLD9
478
53058
F144
Y
W
A
I
S
R
P
F
R
Y
E
R
K
M
T
Rat
Rattus norvegicus
P25115
475
52812
P143
R
Y
W
A
I
S
R
P
F
R
Y
E
R
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521446
353
37571
L46
M
C
S
T
A
S
I
L
H
L
C
L
I
G
L
Chicken
Gallus gallus
XP_426351
648
69599
Y298
A
I
S
S
P
F
R
Y
E
R
K
M
T
Q
R
Frog
Xenopus laevis
P42290
457
51638
A142
I
S
V
D
R
Y
W
A
I
S
S
P
F
R
Y
Zebra Danio
Brachydanio rerio
XP_692025
474
53236
I154
A
S
I
L
N
L
C
I
I
S
V
D
R
Y
W
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
Y147
A
I
S
N
P
F
R
Y
E
R
R
M
T
R
R
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198071
459
51464
L141
S
T
A
S
I
L
N
L
C
V
I
A
V
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
55.1
63.2
N.A.
82.8
82.3
N.A.
43.4
55.2
66.4
54.5
54.9
N.A.
N.A.
N.A.
36.2
Protein Similarity:
100
98.9
70.4
66.8
N.A.
88.9
87.8
N.A.
53.6
62.3
76.7
66.2
68.3
N.A.
N.A.
N.A.
51.3
P-Site Identity:
100
93.3
0
66.6
N.A.
0
13.3
N.A.
6.6
86.6
0
6.6
73.3
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
13.3
86.6
N.A.
26.6
20
N.A.
13.3
93.3
13.3
6.6
93.3
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
0
17
9
9
0
0
17
9
0
0
9
0
0
0
% A
% Cys:
0
9
0
0
0
0
9
0
9
0
9
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
9
0
9
0
% D
% Glu:
9
0
0
0
0
0
0
0
25
0
9
9
0
0
0
% E
% Phe:
0
0
0
0
0
42
0
9
9
9
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
17
34
9
9
17
0
9
9
17
0
17
0
17
0
0
% I
% Lys:
0
0
9
0
0
0
9
0
9
0
34
0
9
9
0
% K
% Leu:
0
9
0
17
0
17
0
17
0
9
0
17
0
0
9
% L
% Met:
9
0
0
9
0
0
0
0
0
0
0
42
0
9
9
% M
% Asn:
0
0
9
9
9
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
42
9
9
9
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% Q
% Arg:
9
9
0
17
9
9
50
0
9
50
9
9
17
17
50
% R
% Ser:
9
17
42
17
9
17
0
0
0
17
9
0
0
9
0
% S
% Thr:
0
9
0
9
9
0
0
0
0
0
0
0
42
0
9
% T
% Val:
0
0
9
0
0
0
0
0
9
9
9
0
9
0
9
% V
% Trp:
0
9
9
0
0
0
9
0
0
0
0
0
0
0
9
% W
% Tyr:
9
9
0
0
0
9
0
42
0
9
9
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _