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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD5
All Species:
25.15
Human Site:
Y396
Identified Species:
50.3
UniProt:
P21918
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21918
NP_000789.1
477
52951
Y396
I
S
N
E
L
I
S
Y
N
Q
D
I
V
F
H
Chimpanzee
Pan troglodytes
XP_528711
477
53003
Y396
I
S
N
E
L
I
S
Y
N
Q
D
I
V
F
H
Rhesus Macaque
Macaca mulatta
O77680
446
49274
S373
N
G
A
A
M
F
S
S
H
H
E
P
R
G
S
Dog
Lupus familis
XP_545942
645
69818
Y565
I
S
N
E
L
I
S
Y
N
Q
D
T
V
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLD9
478
53058
Y391
I
S
N
E
L
I
S
Y
N
Q
D
T
V
F
H
Rat
Rattus norvegicus
P25115
475
52812
Y391
I
S
N
E
L
I
S
Y
N
Q
D
T
V
F
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521446
353
37571
V280
S
G
S
P
G
R
T
V
R
L
S
D
R
L
L
Chicken
Gallus gallus
XP_426351
648
69599
I574
V
N
I
S
N
E
L
I
S
Y
N
Q
D
T
L
Frog
Xenopus laevis
P42290
457
51638
Y382
I
S
N
E
L
I
S
Y
N
Q
D
T
L
F
H
Zebra Danio
Brachydanio rerio
XP_692025
474
53236
Y390
F
S
N
E
L
V
S
Y
H
H
D
T
T
L
Q
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
G386
K
E
P
V
P
G
P
G
A
H
R
L
V
A
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198071
459
51464
D379
K
S
N
H
L
E
T
D
L
K
R
E
E
A
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
55.1
63.2
N.A.
82.8
82.3
N.A.
43.4
55.2
66.4
54.5
54.9
N.A.
N.A.
N.A.
36.2
Protein Similarity:
100
98.9
70.4
66.8
N.A.
88.9
87.8
N.A.
53.6
62.3
76.7
66.2
68.3
N.A.
N.A.
N.A.
51.3
P-Site Identity:
100
100
6.6
86.6
N.A.
93.3
93.3
N.A.
0
0
86.6
46.6
6.6
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
26.6
86.6
N.A.
93.3
93.3
N.A.
13.3
26.6
93.3
60
13.3
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
0
0
0
0
9
0
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
59
9
9
0
0
% D
% Glu:
0
9
0
59
0
17
0
0
0
0
9
9
9
0
0
% E
% Phe:
9
0
0
0
0
9
0
0
0
0
0
0
0
42
0
% F
% Gly:
0
17
0
0
9
9
0
9
0
0
0
0
0
9
0
% G
% His:
0
0
0
9
0
0
0
0
17
25
0
0
0
0
50
% H
% Ile:
50
0
9
0
0
50
0
9
0
0
0
17
0
0
0
% I
% Lys:
17
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
0
0
0
0
67
0
9
0
9
9
0
9
9
25
17
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
67
0
9
0
0
0
50
0
9
0
0
0
0
% N
% Pro:
0
0
9
9
9
0
9
0
0
0
0
9
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
50
0
9
0
0
9
% Q
% Arg:
0
0
0
0
0
9
0
0
9
0
17
0
17
0
0
% R
% Ser:
9
67
9
9
0
0
67
9
9
0
9
0
0
0
9
% S
% Thr:
0
0
0
0
0
0
17
0
0
0
0
42
9
9
0
% T
% Val:
9
0
0
9
0
9
0
9
0
0
0
0
50
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _