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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCKDHB
All Species:
40.61
Human Site:
S227
Identified Species:
63.81
UniProt:
P21953
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21953
NP_000047.1
392
43122
S227
Q
A
K
G
L
L
L
S
C
I
E
D
K
N
P
Chimpanzee
Pan troglodytes
XP_001147610
392
43066
S227
Q
A
K
G
L
L
L
S
C
I
E
D
K
N
P
Rhesus Macaque
Macaca mulatta
XP_001111198
340
37531
E178
G
L
L
L
S
C
I
E
D
K
N
P
C
I
F
Dog
Lupus familis
XP_532213
387
42369
S222
Q
A
K
G
L
L
L
S
C
I
E
D
R
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6P3A8
390
42862
S225
Q
A
K
G
L
L
L
S
C
I
E
D
K
N
P
Rat
Rattus norvegicus
P35738
390
42805
S225
Q
A
K
G
L
L
L
S
C
I
E
D
K
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512570
443
48707
S278
Q
A
K
G
L
L
L
S
C
I
E
D
K
N
P
Chicken
Gallus gallus
NP_989988
392
42727
S227
Q
A
K
G
L
L
L
S
C
I
E
D
K
N
P
Frog
Xenopus laevis
NP_001108310
375
41700
S210
Q
A
K
G
L
L
L
S
C
I
E
D
K
N
P
Zebra Danio
Brachydanio rerio
NP_001074122
391
43009
S226
Q
A
K
G
L
L
L
S
C
I
E
D
K
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001104018
364
40248
A199
K
A
K
G
L
I
L
A
C
I
R
D
P
N
P
Honey Bee
Apis mellifera
XP_392824
374
41532
S209
Q
A
K
G
L
L
L
S
C
I
E
E
P
D
P
Nematode Worm
Caenorhab. elegans
O44451
352
38122
D186
L
K
A
A
I
R
D
D
N
P
V
V
F
L
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38799
363
39157
A192
D
A
R
G
L
L
K
A
A
I
R
D
P
D
P
Baker's Yeast
Sacchar. cerevisiae
P32473
366
40035
A195
D
A
R
G
L
L
K
A
A
I
R
D
P
N
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
85.1
92
N.A.
91
91.8
N.A.
74
83.6
80.8
78
N.A.
58.9
58.9
31.8
N.A.
Protein Similarity:
100
99.4
85.9
95.4
N.A.
93.8
95.1
N.A.
79.6
88.2
87.5
86.7
N.A.
73.4
73.9
48.7
N.A.
P-Site Identity:
100
100
0
93.3
N.A.
100
100
N.A.
100
100
100
100
N.A.
66.6
80
0
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
86.6
93.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.4
34.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.2
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
87
7
7
0
0
0
20
14
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
7
0
0
74
0
0
0
7
0
0
% C
% Asp:
14
0
0
0
0
0
7
7
7
0
0
80
0
14
0
% D
% Glu:
0
0
0
0
0
0
0
7
0
0
67
7
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% F
% Gly:
7
0
0
87
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
7
7
0
0
87
0
0
0
7
0
% I
% Lys:
7
7
74
0
0
0
14
0
0
7
0
0
54
0
0
% K
% Leu:
7
7
7
7
87
80
74
0
0
0
0
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
7
0
0
74
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
0
7
27
0
87
% P
% Gln:
67
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
14
0
0
7
0
0
0
0
20
0
7
0
0
% R
% Ser:
0
0
0
0
7
0
0
67
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _