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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCKDHB
All Species:
36.67
Human Site:
S261
Identified Species:
57.62
UniProt:
P21953
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21953
NP_000047.1
392
43122
S261
E
P
Y
N
I
P
L
S
Q
A
E
V
I
Q
E
Chimpanzee
Pan troglodytes
XP_001147610
392
43066
S261
E
P
Y
N
I
P
L
S
Q
A
E
V
I
Q
E
Rhesus Macaque
Macaca mulatta
XP_001111198
340
37531
Q210
P
Y
N
I
P
L
S
Q
A
E
V
I
Q
E
G
Dog
Lupus familis
XP_532213
387
42369
S256
E
P
Y
N
I
P
L
S
Q
A
E
V
I
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6P3A8
390
42862
S259
E
P
Y
K
I
P
L
S
Q
A
E
V
I
Q
E
Rat
Rattus norvegicus
P35738
390
42805
S259
E
P
Y
K
I
P
L
S
Q
A
E
V
I
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512570
443
48707
S312
D
P
F
Y
I
P
L
S
Q
A
E
V
L
Q
E
Chicken
Gallus gallus
NP_989988
392
42727
S261
E
P
Y
N
I
P
L
S
Q
A
E
V
L
R
Q
Frog
Xenopus laevis
NP_001108310
375
41700
S244
E
P
Y
Y
I
P
L
S
Q
A
E
V
L
Q
E
Zebra Danio
Brachydanio rerio
NP_001074122
391
43009
S260
E
A
Y
Y
I
P
L
S
Q
A
E
V
L
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001104018
364
40248
G233
E
Y
Y
T
S
Q
L
G
K
A
D
I
L
R
H
Honey Bee
Apis mellifera
XP_392824
374
41532
G243
A
D
Y
K
I
E
I
G
K
A
E
I
V
R
E
Nematode Worm
Caenorhab. elegans
O44451
352
38122
G218
D
D
F
V
V
P
I
G
K
A
K
I
E
R
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38799
363
39157
I228
D
S
S
F
C
L
P
I
G
K
A
K
I
E
R
Baker's Yeast
Sacchar. cerevisiae
P32473
366
40035
Y231
S
P
E
F
T
L
P
Y
K
A
K
I
E
R
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
85.1
92
N.A.
91
91.8
N.A.
74
83.6
80.8
78
N.A.
58.9
58.9
31.8
N.A.
Protein Similarity:
100
99.4
85.9
95.4
N.A.
93.8
95.1
N.A.
79.6
88.2
87.5
86.7
N.A.
73.4
73.9
48.7
N.A.
P-Site Identity:
100
100
0
100
N.A.
93.3
93.3
N.A.
73.3
80
86.6
80
N.A.
26.6
33.3
13.3
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
93.3
N.A.
93.3
100
93.3
86.6
N.A.
60
66.6
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.4
34.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.2
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
0
0
7
87
7
0
0
0
7
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
14
0
0
0
0
0
0
0
0
7
0
0
0
0
% D
% Glu:
60
0
7
0
0
7
0
0
0
7
67
0
14
14
67
% E
% Phe:
0
0
14
14
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
20
7
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
7
67
0
14
7
0
0
0
34
40
0
0
% I
% Lys:
0
0
0
20
0
0
0
0
27
7
14
7
0
0
0
% K
% Leu:
0
0
0
0
0
20
67
0
0
0
0
0
34
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
27
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
60
0
0
7
67
14
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
7
60
0
0
0
7
54
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
7
% R
% Ser:
7
7
7
0
7
0
7
60
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
7
7
0
0
0
0
0
7
60
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
14
67
20
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _