KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCKDHB
All Species:
47.58
Human Site:
S318
Identified Species:
74.76
UniProt:
P21953
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21953
NP_000047.1
392
43122
S318
D
V
D
T
I
C
K
S
V
I
K
T
G
R
L
Chimpanzee
Pan troglodytes
XP_001147610
392
43066
S318
D
V
D
T
I
C
K
S
V
I
K
T
G
R
L
Rhesus Macaque
Macaca mulatta
XP_001111198
340
37531
V267
V
D
T
V
C
K
S
V
I
K
T
G
R
L
L
Dog
Lupus familis
XP_532213
387
42369
S313
D
V
D
T
V
C
K
S
V
I
K
T
G
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6P3A8
390
42862
S316
D
V
D
T
V
C
K
S
V
I
K
T
G
R
L
Rat
Rattus norvegicus
P35738
390
42805
S316
D
V
D
T
V
C
K
S
V
I
K
T
G
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512570
443
48707
S369
D
V
E
T
V
C
K
S
V
I
K
T
G
R
L
Chicken
Gallus gallus
NP_989988
392
42727
S318
D
T
E
T
I
C
K
S
V
V
K
T
G
R
L
Frog
Xenopus laevis
NP_001108310
375
41700
S301
D
V
E
T
V
C
K
S
V
T
K
T
G
R
L
Zebra Danio
Brachydanio rerio
NP_001074122
391
43009
S317
D
K
E
T
V
C
K
S
V
M
K
T
G
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001104018
364
40248
S290
D
A
I
T
I
C
T
S
A
K
K
T
G
R
V
Honey Bee
Apis mellifera
XP_392824
374
41532
S300
D
T
E
L
V
C
K
S
V
K
K
T
G
R
V
Nematode Worm
Caenorhab. elegans
O44451
352
38122
V275
F
E
S
I
R
Q
S
V
H
K
T
H
H
L
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38799
363
39157
S285
D
R
A
T
I
N
A
S
V
R
K
T
S
R
L
Baker's Yeast
Sacchar. cerevisiae
P32473
366
40035
T288
D
T
E
A
I
I
K
T
V
K
K
T
N
H
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
85.1
92
N.A.
91
91.8
N.A.
74
83.6
80.8
78
N.A.
58.9
58.9
31.8
N.A.
Protein Similarity:
100
99.4
85.9
95.4
N.A.
93.8
95.1
N.A.
79.6
88.2
87.5
86.7
N.A.
73.4
73.9
48.7
N.A.
P-Site Identity:
100
100
6.6
93.3
N.A.
93.3
93.3
N.A.
86.6
80
80
73.3
N.A.
60
60
0
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
100
93.3
93.3
93.3
N.A.
66.6
80
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.4
34.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.2
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
7
0
0
7
0
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
7
74
0
0
0
0
0
0
0
0
0
% C
% Asp:
87
7
34
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
7
40
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
7
74
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
7
7
7
0
% H
% Ile:
0
0
7
7
40
7
0
0
7
40
0
0
0
0
0
% I
% Lys:
0
7
0
0
0
7
74
0
0
34
87
0
0
0
0
% K
% Leu:
0
0
0
7
0
0
0
0
0
0
0
0
0
14
80
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
0
7
0
0
0
0
7
0
0
7
80
0
% R
% Ser:
0
0
7
0
0
0
14
80
0
0
0
0
7
0
0
% S
% Thr:
0
20
7
74
0
0
7
7
0
7
14
87
0
0
0
% T
% Val:
7
47
0
7
47
0
0
14
80
7
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _