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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCKDHB All Species: 40.34
Human Site: Y392 Identified Species: 63.39
UniProt: P21953 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P21953 NP_000047.1 392 43122 Y392 A L R K M I N Y _ _ _ _ _ _ _
Chimpanzee Pan troglodytes XP_001147610 392 43066 Y392 A L R K M I N Y _ _ _ _ _ _ _
Rhesus Macaque Macaca mulatta XP_001111198 340 37531
Dog Lupus familis XP_532213 387 42369 Y387 A L R K M I N Y _ _ _ _ _ _ _
Cat Felis silvestris
Mouse Mus musculus Q6P3A8 390 42862 Y390 A L R K M I N Y _ _ _ _ _ _ _
Rat Rattus norvegicus P35738 390 42805 Y390 A L R K M I N Y _ _ _ _ _ _ _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512570 443 48707 Y443 A L R K M I N Y _ _ _ _ _ _ _
Chicken Gallus gallus NP_989988 392 42727 Y392 A L R K M I N Y _ _ _ _ _ _ _
Frog Xenopus laevis NP_001108310 375 41700 Y375 A L R K M I N Y _ _ _ _ _ _ _
Zebra Danio Brachydanio rerio NP_001074122 391 43009 Y391 A V K R M I N Y _ _ _ _ _ _ _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001104018 364 40248 F364 A I N D I V N F _ _ _ _ _ _ _
Honey Bee Apis mellifera XP_392824 374 41532 Y374 A V K N I L N Y _ _ _ _ _ _ _
Nematode Worm Caenorhab. elegans O44451 352 38122 L349 V K A V K K S L N I A _ _ _ _
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38799 363 39157 C359 V R A S K R A C Y R S K _ _ _
Baker's Yeast Sacchar. cerevisiae P32473 366 40035 V362 I V K A V K E V L S I E _ _ _
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 85.1 92 N.A. 91 91.8 N.A. 74 83.6 80.8 78 N.A. 58.9 58.9 31.8 N.A.
Protein Similarity: 100 99.4 85.9 95.4 N.A. 93.8 95.1 N.A. 79.6 88.2 87.5 86.7 N.A. 73.4 73.9 48.7 N.A.
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 100 100 100 62.5 N.A. 25 37.5 0 N.A.
P-Site Similarity: 100 100 0 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 75 87.5 18.1 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 32.4 34.1 N.A.
Protein Similarity: N.A. N.A. N.A. 50.2 52 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 8.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 74 0 14 7 0 0 7 0 0 0 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 7 0 0 0 0 7 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 7 0 0 14 60 0 0 0 7 7 0 0 0 0 % I
% Lys: 0 7 20 54 14 14 0 0 0 0 0 7 0 0 0 % K
% Leu: 0 54 0 0 0 7 0 7 7 0 0 0 0 0 0 % L
% Met: 0 0 0 0 60 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 7 0 0 74 0 7 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 7 54 7 0 7 0 0 0 7 0 0 0 0 0 % R
% Ser: 0 0 0 7 0 0 7 0 0 7 7 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 14 20 0 7 7 7 0 7 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 67 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 74 74 74 80 94 94 94 % _