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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCKDHB All Species: 27.88
Human Site: Y65 Identified Species: 43.81
UniProt: P21953 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P21953 NP_000047.1 392 43122 Y65 P D P E P R E Y G Q T Q K M N
Chimpanzee Pan troglodytes XP_001147610 392 43066 Y65 P D P E P R E Y G Q T Q K M N
Rhesus Macaque Macaca mulatta XP_001111198 340 37531 W23 A A G A E G H W R R F R G V G
Dog Lupus familis XP_532213 387 42369 Y60 P D P E P Q E Y G Q T Q K M N
Cat Felis silvestris
Mouse Mus musculus Q6P3A8 390 42862 Y63 P D P E S L Q Y G Q T Q K M N
Rat Rattus norvegicus P35738 390 42805 Y63 P D P E S L Q Y G Q T Q K M N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512570 443 48707 C116 R H G G P S F C G E T Q K M N
Chicken Gallus gallus NP_989988 392 42727 Y65 P D P A P S A Y G Q T Q K M N
Frog Xenopus laevis NP_001108310 375 41700 Y48 P D P E P T H Y G T T Q K M N
Zebra Danio Brachydanio rerio NP_001074122 391 43009 Y64 P D P V P T Q Y G P T Q K M N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001104018 364 40248 M37 F T Y Y P T R M G T G K R M N
Honey Bee Apis mellifera XP_392824 374 41532 P47 T D K S K N I P G E T E K M N
Nematode Worm Caenorhab. elegans O44451 352 38122 L31 T M T V R D A L N Q A M D E E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38799 363 39157 A33 A R S Y A A G A K E M T V R D
Baker's Yeast Sacchar. cerevisiae P32473 366 40035 F33 A A A A A L R F S S T K T M T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 85.1 92 N.A. 91 91.8 N.A. 74 83.6 80.8 78 N.A. 58.9 58.9 31.8 N.A.
Protein Similarity: 100 99.4 85.9 95.4 N.A. 93.8 95.1 N.A. 79.6 88.2 87.5 86.7 N.A. 73.4 73.9 48.7 N.A.
P-Site Identity: 100 100 0 93.3 N.A. 80 80 N.A. 46.6 80 80 73.3 N.A. 26.6 40 6.6 N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 86.6 86.6 N.A. 53.3 80 80 80 N.A. 40 53.3 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 32.4 34.1 N.A.
Protein Similarity: N.A. N.A. N.A. 50.2 52 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 14 7 20 14 7 14 7 0 0 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 60 0 0 0 7 0 0 0 0 0 0 7 0 7 % D
% Glu: 0 0 0 40 7 0 20 0 0 20 0 7 0 7 7 % E
% Phe: 7 0 0 0 0 0 7 7 0 0 7 0 0 0 0 % F
% Gly: 0 0 14 7 0 7 7 0 74 0 7 0 7 0 7 % G
% His: 0 7 0 0 0 0 14 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 7 0 7 0 0 0 7 0 0 14 67 0 0 % K
% Leu: 0 0 0 0 0 20 0 7 0 0 0 0 0 0 0 % L
% Met: 0 7 0 0 0 0 0 7 0 0 7 7 0 80 0 % M
% Asn: 0 0 0 0 0 7 0 0 7 0 0 0 0 0 74 % N
% Pro: 54 0 54 0 54 0 0 7 0 7 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 20 0 0 47 0 60 0 0 0 % Q
% Arg: 7 7 0 0 7 14 14 0 7 7 0 7 7 7 0 % R
% Ser: 0 0 7 7 14 14 0 0 7 7 0 0 0 0 0 % S
% Thr: 14 7 7 0 0 20 0 0 0 14 74 7 7 0 7 % T
% Val: 0 0 0 14 0 0 0 0 0 0 0 0 7 7 0 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 14 0 0 0 54 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _