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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BMP6
All Species:
16.67
Human Site:
S399
Identified Species:
36.67
UniProt:
P22004
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22004
NP_001709.1
513
57226
S399
Q
D
V
A
R
V
S
S
A
S
D
Y
N
S
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085364
511
56715
S397
Q
D
V
A
R
V
S
S
A
S
D
Y
N
S
S
Dog
Lupus familis
XP_535880
720
80058
S606
Q
D
V
S
R
V
S
S
A
S
D
Y
N
S
S
Cat
Felis silvestris
Mouse
Mus musculus
P20722
510
56413
G396
Q
D
V
S
R
G
S
G
S
S
D
Y
N
G
S
Rat
Rattus norvegicus
Q04906
506
56204
S392
Q
D
V
S
R
G
S
S
A
S
D
Y
N
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510324
430
49386
S321
M
S
N
I
A
E
N
S
S
S
D
Q
R
Q
A
Chicken
Gallus gallus
Q90752
405
46039
H296
A
R
R
S
P
K
H
H
G
S
R
K
N
K
K
Frog
Xenopus laevis
P30886
426
48946
K317
D
G
I
M
P
P
G
K
R
R
F
L
K
Q
A
Zebra Danio
Brachydanio rerio
P35621
355
40183
L246
K
R
S
A
S
Y
Y
L
P
V
T
P
S
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P27091
455
51669
N341
K
K
S
V
S
P
N
N
V
P
L
L
E
P
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48969
461
51863
S347
D
T
D
N
D
I
A
S
R
D
S
A
S
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.4
53.3
N.A.
91.2
90.4
N.A.
54.9
29
46.7
27.1
N.A.
31.7
N.A.
N.A.
34.1
Protein Similarity:
100
N.A.
97.6
60.2
N.A.
93.5
92.7
N.A.
68.4
41.3
62.3
40.7
N.A.
49.3
N.A.
N.A.
52
P-Site Identity:
100
N.A.
100
93.3
N.A.
66.6
86.6
N.A.
20
13.3
0
6.6
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
80
93.3
N.A.
40
20
13.3
26.6
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
28
10
0
10
0
37
0
0
10
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
46
10
0
10
0
0
0
0
10
55
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
10
0
0
0
19
10
10
10
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
10
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
19
10
0
0
0
10
0
10
0
0
0
10
10
10
10
% K
% Leu:
0
0
0
0
0
0
0
10
0
0
10
19
0
0
10
% L
% Met:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
10
10
0
0
19
10
0
0
0
0
55
10
0
% N
% Pro:
0
0
0
0
19
19
0
0
10
10
0
10
0
10
0
% P
% Gln:
46
0
0
0
0
0
0
0
0
0
0
10
0
19
0
% Q
% Arg:
0
19
10
0
46
0
0
0
19
10
10
0
10
0
0
% R
% Ser:
0
10
19
37
19
0
46
55
19
64
10
0
19
46
46
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
46
10
0
28
0
0
10
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
10
0
0
0
0
46
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _