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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MUT
All Species:
18.18
Human Site:
S523
Identified Species:
40
UniProt:
P22033
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22033
NP_000246.2
750
83120
S523
E
K
L
K
K
I
K
S
S
R
D
Q
A
L
A
Chimpanzee
Pan troglodytes
XP_001146810
750
83144
S523
E
K
L
K
K
I
K
S
S
R
D
Q
A
L
A
Rhesus Macaque
Macaca mulatta
XP_001104455
750
83078
S523
E
K
L
Q
K
I
K
S
S
R
D
Q
A
L
A
Dog
Lupus familis
XP_532164
903
99800
A676
E
K
L
K
K
V
K
A
I
R
D
Q
D
L
A
Cat
Felis silvestris
Mouse
Mus musculus
P16332
748
82947
S521
E
K
L
K
K
I
K
S
S
R
D
Q
A
L
A
Rat
Rattus norvegicus
XP_002727217
748
82907
S521
E
K
L
K
K
I
K
S
S
R
D
Q
A
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510860
750
82679
A523
E
K
L
K
K
V
K
A
S
R
D
Q
A
A
A
Chicken
Gallus gallus
XP_420055
748
82747
A521
E
K
I
N
K
V
K
A
S
R
D
P
A
A
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001092696
757
83499
E530
E
K
L
Q
K
V
R
E
S
R
D
A
E
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23381
744
81665
R514
C
A
K
L
N
H
I
R
A
T
R
D
A
E
K
Sea Urchin
Strong. purpuratus
XP_781852
767
85131
K540
I
N
K
L
K
D
I
K
Q
S
R
S
S
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.8
78.9
N.A.
92.5
95
N.A.
89.8
87.5
N.A.
80.7
N.A.
N.A.
N.A.
69.3
70.6
Protein Similarity:
100
100
99.5
81.5
N.A.
96.1
97.8
N.A.
95.5
94.5
N.A.
89.1
N.A.
N.A.
N.A.
81.7
83.7
P-Site Identity:
100
100
93.3
73.3
N.A.
100
100
N.A.
80
60
N.A.
53.3
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
93.3
80
N.A.
73.3
N.A.
N.A.
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
28
10
0
0
10
73
28
82
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
82
10
10
0
0
% D
% Glu:
82
0
0
0
0
0
0
10
0
0
0
0
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
0
0
46
19
0
10
0
0
0
0
0
0
% I
% Lys:
0
82
19
55
91
0
73
10
0
0
0
0
0
0
10
% K
% Leu:
0
0
73
19
0
0
0
0
0
0
0
0
0
55
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
19
0
0
0
0
10
0
0
64
0
10
0
% Q
% Arg:
0
0
0
0
0
0
10
10
0
82
19
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
46
73
10
0
10
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
37
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _