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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MUT All Species: 43.33
Human Site: S584 Identified Species: 95.33
UniProt: P22033 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22033 NP_000246.2 750 83120 S584 K A N D R M V S G A Y R Q E F
Chimpanzee Pan troglodytes XP_001146810 750 83144 S584 K A N D R M V S G A Y R Q E F
Rhesus Macaque Macaca mulatta XP_001104455 750 83078 S584 K A N D R M V S G A Y R Q E F
Dog Lupus familis XP_532164 903 99800 S737 K A N D R M V S G A Y R Q E F
Cat Felis silvestris
Mouse Mus musculus P16332 748 82947 S582 K A N D R M V S G A Y R Q E F
Rat Rattus norvegicus XP_002727217 748 82907 S582 K A N D R M V S G A Y R Q E F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510860 750 82679 S584 K A S D R M V S G A Y R Q E F
Chicken Gallus gallus XP_420055 748 82747 S582 K A S D R M V S G A Y R Q E F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001092696 757 83499 S591 K A S T R M V S G A Y R S E F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q23381 744 81665 S575 A A V N R L V S G A Y K S E F
Sea Urchin Strong. purpuratus XP_781852 767 85131 S601 V A S D R M V S G A Y K S E Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.8 78.9 N.A. 92.5 95 N.A. 89.8 87.5 N.A. 80.7 N.A. N.A. N.A. 69.3 70.6
Protein Similarity: 100 100 99.5 81.5 N.A. 96.1 97.8 N.A. 95.5 94.5 N.A. 89.1 N.A. N.A. N.A. 81.7 83.7
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 N.A. 80 N.A. N.A. N.A. 60 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 N.A. 86.6 N.A. N.A. N.A. 80 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 100 0 0 0 0 0 0 0 100 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 82 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 91 % F
% Gly: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 82 0 0 0 0 0 0 0 0 0 0 19 0 0 0 % K
% Leu: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 91 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 55 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 73 0 0 % Q
% Arg: 0 0 0 0 100 0 0 0 0 0 0 82 0 0 0 % R
% Ser: 0 0 37 0 0 0 0 100 0 0 0 0 28 0 0 % S
% Thr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 10 0 10 0 0 0 100 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _