KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MUT
All Species:
43.64
Human Site:
T249
Identified Species:
96
UniProt:
P22033
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22033
NP_000246.2
750
83120
T249
I
A
D
I
F
E
Y
T
A
K
H
M
P
K
F
Chimpanzee
Pan troglodytes
XP_001146810
750
83144
T249
I
A
D
I
F
E
Y
T
A
K
H
M
P
K
F
Rhesus Macaque
Macaca mulatta
XP_001104455
750
83078
T249
I
A
D
I
F
Q
Y
T
S
K
H
M
P
K
F
Dog
Lupus familis
XP_532164
903
99800
T402
I
A
D
I
F
Q
Y
T
A
Q
H
M
P
K
F
Cat
Felis silvestris
Mouse
Mus musculus
P16332
748
82947
T247
I
A
D
I
F
Q
Y
T
A
Q
H
M
P
K
F
Rat
Rattus norvegicus
XP_002727217
748
82907
T247
I
A
D
I
F
Q
Y
T
A
Q
H
M
P
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510860
750
82679
T249
I
A
D
I
F
Q
Y
T
A
K
H
M
P
R
F
Chicken
Gallus gallus
XP_420055
748
82747
T247
I
A
D
I
F
Q
Y
T
S
K
Y
M
P
K
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001092696
757
83499
T256
I
A
D
I
F
A
Y
T
S
K
N
M
P
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23381
744
81665
T241
I
G
D
I
F
A
Y
T
S
R
E
M
P
K
F
Sea Urchin
Strong. purpuratus
XP_781852
767
85131
T267
I
G
D
I
F
A
Y
T
S
Q
H
M
P
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.8
78.9
N.A.
92.5
95
N.A.
89.8
87.5
N.A.
80.7
N.A.
N.A.
N.A.
69.3
70.6
Protein Similarity:
100
100
99.5
81.5
N.A.
96.1
97.8
N.A.
95.5
94.5
N.A.
89.1
N.A.
N.A.
N.A.
81.7
83.7
P-Site Identity:
100
100
86.6
86.6
N.A.
86.6
86.6
N.A.
86.6
80
N.A.
80
N.A.
N.A.
N.A.
66.6
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
N.A.
80
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
82
0
0
0
28
0
0
55
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
19
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
100
% F
% Gly:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
73
0
0
0
0
% H
% Ile:
100
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
55
0
0
0
91
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% P
% Gln:
0
0
0
0
0
55
0
0
0
37
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
0
46
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
100
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _