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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OSBP
All Species:
20.91
Human Site:
Y573
Identified Species:
38.33
UniProt:
P22059
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22059
NP_002547.1
807
89421
Y573
F
H
A
T
G
H
H
Y
T
W
K
K
V
T
T
Chimpanzee
Pan troglodytes
XP_508451
807
89429
Y573
F
H
A
T
G
H
H
Y
T
W
K
K
V
T
T
Rhesus Macaque
Macaca mulatta
XP_001090190
805
89207
Y571
F
H
A
T
G
H
H
Y
T
W
K
K
V
T
T
Dog
Lupus familis
XP_540566
1109
121200
Y875
F
H
A
T
G
H
H
Y
T
W
K
K
V
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3B7Z2
751
84671
K533
V
H
N
I
I
V
G
K
L
W
I
D
Q
S
G
Rat
Rattus norvegicus
Q8K4M9
950
107747
Y703
L
L
E
H
N
E
A
Y
T
W
T
N
P
T
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505999
738
84284
N533
S
G
E
I
D
I
V
N
H
K
T
G
D
K
C
Chicken
Gallus gallus
XP_415293
788
88247
Y553
F
H
S
S
G
N
H
Y
V
W
R
K
V
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139057
760
85799
I541
I
I
V
G
K
L
W
I
D
Q
S
G
E
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477271
784
89306
S554
P
N
S
G
R
R
Y
S
W
R
K
V
T
T
T
Honey Bee
Apis mellifera
XP_392480
836
95642
W609
D
G
T
H
H
Y
T
W
R
K
V
T
T
T
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790853
566
64483
N368
S
R
I
P
M
P
V
N
F
N
E
P
L
S
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35845
1188
135079
P954
P
D
H
N
I
S
V
P
E
E
T
Y
S
W
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
71.2
N.A.
90.5
29.4
N.A.
83.8
68.9
N.A.
68.4
N.A.
34.3
49.6
N.A.
42.8
Protein Similarity:
100
100
99.7
72.3
N.A.
91.9
42.8
N.A.
86.4
78.9
N.A.
78
N.A.
50.9
64
N.A.
52.9
P-Site Identity:
100
100
100
100
N.A.
13.3
26.6
N.A.
0
60
N.A.
0
N.A.
20
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
20
26.6
N.A.
0
93.3
N.A.
0
N.A.
40
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
31
0
0
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% C
% Asp:
8
8
0
0
8
0
0
0
8
0
0
8
8
0
8
% D
% Glu:
0
0
16
0
0
8
0
0
8
8
8
0
8
0
0
% E
% Phe:
39
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
16
0
16
39
0
8
0
0
0
0
16
0
0
8
% G
% His:
0
47
8
16
8
31
39
0
8
0
0
0
0
0
0
% H
% Ile:
8
8
8
16
16
8
0
8
0
0
8
0
0
8
0
% I
% Lys:
0
0
0
0
8
0
0
8
0
16
39
39
0
8
8
% K
% Leu:
8
8
0
0
0
8
0
0
8
0
0
0
8
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
8
8
8
8
8
0
16
0
8
0
8
0
0
0
% N
% Pro:
16
0
0
8
0
8
0
8
0
0
0
8
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% Q
% Arg:
0
8
0
0
8
8
0
0
8
8
8
0
0
0
0
% R
% Ser:
16
0
16
8
0
8
0
8
0
0
8
0
8
16
8
% S
% Thr:
0
0
8
31
0
0
8
0
39
0
24
8
16
62
39
% T
% Val:
8
0
8
0
0
8
24
0
8
0
8
8
39
0
8
% V
% Trp:
0
0
0
0
0
0
8
8
8
54
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
8
8
47
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _