KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OSBP
All Species:
26.36
Human Site:
Y764
Identified Species:
48.33
UniProt:
P22059
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22059
NP_002547.1
807
89421
Y764
A
T
E
D
G
T
P
Y
D
P
Y
K
A
L
W
Chimpanzee
Pan troglodytes
XP_508451
807
89429
Y764
A
T
E
D
G
T
P
Y
D
P
Y
K
A
L
W
Rhesus Macaque
Macaca mulatta
XP_001090190
805
89207
Y762
A
T
E
D
G
T
P
Y
D
P
Y
K
A
L
W
Dog
Lupus familis
XP_540566
1109
121200
Y1066
A
T
E
D
G
T
P
Y
D
P
Y
K
A
L
W
Cat
Felis silvestris
Mouse
Mus musculus
Q3B7Z2
751
84671
H708
A
T
E
D
G
T
P
H
D
P
Y
K
A
L
W
Rat
Rattus norvegicus
Q8K4M9
950
107747
R907
Q
R
A
A
R
K
N
R
S
K
S
E
E
D
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505999
738
84284
Y695
A
T
E
D
G
T
P
Y
D
P
Y
K
A
L
W
Chicken
Gallus gallus
XP_415293
788
88247
Y745
A
L
E
E
G
K
D
Y
E
G
Y
I
P
L
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139057
760
85799
Q717
N
P
E
E
G
G
H
Q
D
S
Y
K
A
M
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477271
784
89306
Y741
A
A
A
E
G
R
P
Y
P
A
Y
E
P
M
W
Honey Bee
Apis mellifera
XP_392480
836
95642
Y793
A
A
A
Q
G
L
P
Y
E
T
Y
E
P
L
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790853
566
64483
G524
K
L
W
V
D
Q
S
G
E
C
E
L
L
N
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35845
1188
135079
G1145
K
K
E
R
E
Q
K
G
E
E
Y
R
P
K
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
71.2
N.A.
90.5
29.4
N.A.
83.8
68.9
N.A.
68.4
N.A.
34.3
49.6
N.A.
42.8
Protein Similarity:
100
100
99.7
72.3
N.A.
91.9
42.8
N.A.
86.4
78.9
N.A.
78
N.A.
50.9
64
N.A.
52.9
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
100
46.6
N.A.
46.6
N.A.
40
46.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
60
N.A.
60
N.A.
60
60
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
16
24
8
0
0
0
0
0
8
0
0
54
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
47
8
0
8
0
54
0
0
0
0
8
0
% D
% Glu:
0
0
70
24
8
0
0
0
31
8
8
24
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
77
8
0
16
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
16
8
0
0
0
16
8
0
0
8
0
54
0
8
0
% K
% Leu:
0
16
0
0
0
8
0
0
0
0
0
8
8
62
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% M
% Asn:
8
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
0
0
0
0
62
0
8
47
0
0
31
0
0
% P
% Gln:
8
0
0
8
0
16
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
8
8
8
0
8
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
0
8
8
8
0
0
0
0
% S
% Thr:
0
47
0
0
0
47
0
0
0
8
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
93
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
85
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _