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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBL
All Species:
48.79
Human Site:
S116
Identified Species:
71.56
UniProt:
P22087
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22087
NP_001427.2
321
33784
S116
K
N
L
V
P
G
E
S
V
Y
G
E
K
R
V
Chimpanzee
Pan troglodytes
XP_001135914
299
31246
L106
C
R
G
K
E
D
A
L
V
T
K
N
L
V
P
Rhesus Macaque
Macaca mulatta
XP_001088664
401
42281
S195
K
N
L
V
P
G
E
S
V
Y
G
E
K
R
V
Dog
Lupus familis
XP_533671
313
33300
S108
K
N
L
V
P
G
E
S
V
Y
G
E
K
R
V
Cat
Felis silvestris
Mouse
Mus musculus
P35550
327
34288
S122
K
N
L
V
P
G
E
S
V
Y
G
E
K
R
V
Rat
Rattus norvegicus
P22509
327
34203
S122
K
N
L
V
P
G
E
S
V
Y
G
E
K
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517295
252
27451
S61
K
N
M
V
P
G
E
S
V
Y
G
E
K
R
I
Chicken
Gallus gallus
Frog
Xenopus laevis
P22232
323
34313
S118
K
N
L
V
P
G
E
S
V
Y
G
E
K
R
I
Zebra Danio
Brachydanio rerio
NP_998167
317
33615
S112
K
N
M
V
I
G
E
S
V
Y
G
E
K
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1V3
344
34618
E141
R
N
F
V
P
G
S
E
V
Y
G
E
K
R
I
Honey Bee
Apis mellifera
XP_624378
310
32283
V105
N
L
V
P
G
S
E
V
Y
G
E
K
R
I
S
Nematode Worm
Caenorhab. elegans
Q22053
352
36364
S147
K
N
M
V
V
G
E
S
V
Y
G
E
K
R
V
Sea Urchin
Strong. purpuratus
XP_001175797
311
32878
S107
K
N
L
V
P
G
E
S
V
Y
G
E
K
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FEF8
308
32811
A99
K
N
L
V
P
G
E
A
V
Y
N
E
K
R
I
Baker's Yeast
Sacchar. cerevisiae
P15646
327
34447
S116
K
N
M
A
P
G
E
S
V
Y
G
E
K
R
I
Red Bread Mold
Neurospora crassa
Q9HE26
323
33794
S111
V
N
L
V
P
G
E
S
V
Y
G
E
K
R
I
Conservation
Percent
Protein Identity:
100
91.9
77.5
96.8
N.A.
96
95.4
N.A.
71
N.A.
82
81.3
N.A.
76.1
77.5
67.9
80
Protein Similarity:
100
92.2
78.5
96.8
N.A.
96
95.4
N.A.
74.7
N.A.
88.2
86.5
N.A.
81.9
84.1
76.4
85.6
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
86.6
N.A.
93.3
80
N.A.
66.6
6.6
86.6
93.3
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
100
N.A.
100
93.3
N.A.
80
26.6
93.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
71.3
66
66.5
Protein Similarity:
N.A.
N.A.
N.A.
78.8
76.4
76.7
P-Site Identity:
N.A.
N.A.
N.A.
80
80
86.6
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
93.3
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
7
7
0
0
0
0
0
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
7
0
88
7
0
0
7
88
0
0
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
7
88
0
0
0
7
82
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
50
% I
% Lys:
75
0
0
7
0
0
0
0
0
0
7
7
88
0
0
% K
% Leu:
0
7
57
0
0
0
0
7
0
0
0
0
7
0
0
% L
% Met:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
88
0
0
0
0
0
0
0
0
7
7
0
0
0
% N
% Pro:
0
0
0
7
75
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
7
0
0
0
0
0
0
0
0
0
0
7
88
0
% R
% Ser:
0
0
0
0
0
7
7
75
0
0
0
0
0
0
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% T
% Val:
7
0
7
82
7
0
0
7
94
0
0
0
0
7
38
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
88
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _