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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBL
All Species:
45.76
Human Site:
S124
Identified Species:
67.11
UniProt:
P22087
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22087
NP_001427.2
321
33784
S124
V
Y
G
E
K
R
V
S
I
S
E
G
D
D
K
Chimpanzee
Pan troglodytes
XP_001135914
299
31246
G114
V
T
K
N
L
V
P
G
E
S
V
Y
G
E
K
Rhesus Macaque
Macaca mulatta
XP_001088664
401
42281
S203
V
Y
G
E
K
R
V
S
I
S
E
G
D
D
K
Dog
Lupus familis
XP_533671
313
33300
S116
V
Y
G
E
K
R
V
S
I
S
E
G
D
D
K
Cat
Felis silvestris
Mouse
Mus musculus
P35550
327
34288
S130
V
Y
G
E
K
R
V
S
I
S
E
G
D
D
K
Rat
Rattus norvegicus
P22509
327
34203
S130
V
Y
G
E
K
R
V
S
I
S
E
G
D
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517295
252
27451
S69
V
Y
G
E
K
R
I
S
V
E
D
G
E
V
K
Chicken
Gallus gallus
Frog
Xenopus laevis
P22232
323
34313
S126
V
Y
G
E
K
R
I
S
V
E
D
G
E
V
K
Zebra Danio
Brachydanio rerio
NP_998167
317
33615
N120
V
Y
G
E
K
R
I
N
V
E
E
G
E
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1V3
344
34618
S149
V
Y
G
E
K
R
I
S
V
E
T
N
G
E
K
Honey Bee
Apis mellifera
XP_624378
310
32283
V113
Y
G
E
K
R
I
S
V
E
G
E
N
G
E
K
Nematode Worm
Caenorhab. elegans
Q22053
352
36364
S155
V
Y
G
E
K
R
V
S
V
D
D
G
A
G
S
Sea Urchin
Strong. purpuratus
XP_001175797
311
32878
S115
V
Y
G
E
K
R
I
S
I
E
E
G
E
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FEF8
308
32811
S107
V
Y
N
E
K
R
I
S
V
Q
N
E
D
G
T
Baker's Yeast
Sacchar. cerevisiae
P15646
327
34447
S124
V
Y
G
E
K
R
I
S
V
E
E
P
S
K
E
Red Bread Mold
Neurospora crassa
Q9HE26
323
33794
S119
V
Y
G
E
K
R
I
S
V
E
N
A
S
K
E
Conservation
Percent
Protein Identity:
100
91.9
77.5
96.8
N.A.
96
95.4
N.A.
71
N.A.
82
81.3
N.A.
76.1
77.5
67.9
80
Protein Similarity:
100
92.2
78.5
96.8
N.A.
96
95.4
N.A.
74.7
N.A.
88.2
86.5
N.A.
81.9
84.1
76.4
85.6
P-Site Identity:
100
20
100
100
N.A.
100
100
N.A.
60
N.A.
60
60
N.A.
53.3
13.3
60
73.3
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
86.6
N.A.
86.6
86.6
N.A.
73.3
33.3
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
71.3
66
66.5
Protein Similarity:
N.A.
N.A.
N.A.
78.8
76.4
76.7
P-Site Identity:
N.A.
N.A.
N.A.
46.6
53.3
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
60
73.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
19
0
38
32
0
% D
% Glu:
0
0
7
88
0
0
0
0
13
44
57
7
25
19
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
82
0
0
0
0
7
0
7
0
63
19
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
50
0
38
0
0
0
0
0
0
% I
% Lys:
0
0
7
7
88
0
0
0
0
0
0
0
0
19
75
% K
% Leu:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
7
0
0
0
7
0
0
13
13
0
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
0
0
7
88
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
7
82
0
38
0
0
13
0
7
% S
% Thr:
0
7
0
0
0
0
0
0
0
0
7
0
0
7
7
% T
% Val:
94
0
0
0
0
7
38
7
50
0
7
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
88
0
0
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _