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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBL All Species: 19.09
Human Site: S126 Identified Species: 28
UniProt: P22087 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.53
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22087 NP_001427.2 321 33784 S126 G E K R V S I S E G D D K I E
Chimpanzee Pan troglodytes XP_001135914 299 31246 S116 K N L V P G E S V Y G E K R V
Rhesus Macaque Macaca mulatta XP_001088664 401 42281 S205 G E K R V S I S E G D D K I E
Dog Lupus familis XP_533671 313 33300 S118 G E K R V S I S E G D D K I E
Cat Felis silvestris
Mouse Mus musculus P35550 327 34288 S132 G E K R V S I S E G D D K I E
Rat Rattus norvegicus P22509 327 34203 S132 G E K R V S I S E G D D K I E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517295 252 27451 E71 G E K R I S V E D G E V K L E
Chicken Gallus gallus
Frog Xenopus laevis P22232 323 34313 E128 G E K R I S V E D G E V K T E
Zebra Danio Brachydanio rerio NP_998167 317 33615 E122 G E K R I N V E E G E T K I E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1V3 344 34618 E151 G E K R I S V E T N G E K I E
Honey Bee Apis mellifera XP_624378 310 32283 G115 E K R I S V E G E N G E K I E
Nematode Worm Caenorhab. elegans Q22053 352 36364 D157 G E K R V S V D D G A G S I E
Sea Urchin Strong. purpuratus XP_001175797 311 32878 E117 G E K R I S I E E G E K K L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FEF8 308 32811 Q109 N E K R I S V Q N E D G T K V
Baker's Yeast Sacchar. cerevisiae P15646 327 34447 E126 G E K R I S V E E P S K E D G
Red Bread Mold Neurospora crassa Q9HE26 323 33794 E121 G E K R I S V E N A S K E E G
Conservation
Percent
Protein Identity: 100 91.9 77.5 96.8 N.A. 96 95.4 N.A. 71 N.A. 82 81.3 N.A. 76.1 77.5 67.9 80
Protein Similarity: 100 92.2 78.5 96.8 N.A. 96 95.4 N.A. 74.7 N.A. 88.2 86.5 N.A. 81.9 84.1 76.4 85.6
P-Site Identity: 100 13.3 100 100 N.A. 100 100 N.A. 53.3 N.A. 53.3 60 N.A. 53.3 26.6 60 66.6
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 86.6 N.A. 80 86.6 N.A. 73.3 46.6 73.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. 71.3 66 66.5
Protein Similarity: N.A. N.A. N.A. 78.8 76.4 76.7
P-Site Identity: N.A. N.A. N.A. 33.3 40 33.3
P-Site Similarity: N.A. N.A. N.A. 46.6 60 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 7 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 19 0 38 32 0 7 0 % D
% Glu: 7 88 0 0 0 0 13 44 57 7 25 19 13 7 75 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 82 0 0 0 0 7 0 7 0 63 19 13 0 0 13 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 50 0 38 0 0 0 0 0 0 57 0 % I
% Lys: 7 7 88 0 0 0 0 0 0 0 0 19 75 7 0 % K
% Leu: 0 0 7 0 0 0 0 0 0 0 0 0 0 13 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 7 0 0 0 7 0 0 13 13 0 0 0 0 0 % N
% Pro: 0 0 0 0 7 0 0 0 0 7 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % Q
% Arg: 0 0 7 88 0 0 0 0 0 0 0 0 0 7 0 % R
% Ser: 0 0 0 0 7 82 0 38 0 0 13 0 7 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 7 0 0 7 7 7 0 % T
% Val: 0 0 0 7 38 7 50 0 7 0 0 13 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _