Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBL All Species: 19.7
Human Site: S66 Identified Species: 28.89
UniProt: P22087 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.4
Phosphosite
Sequences
Species Species
Scientific Name		 UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22087 NP_001427.2 321 33784 S66 R G G G G F H S G G N R G R G
Chimpanzee Pan troglodytes XP_001135914 299 31246 S66 R G G G G F H S G G N R G R G
Rhesus Macaque Macaca mulatta XP_001088664 401 42281 S145 G R G G G F H S G G N R G R G
Dog Lupus familis XP_533671 313 33300 S58 R G G G G F Q S G G N R G R G
Cat Felis silvestris
Mouse Mus musculus P35550 327 34288 S70 G R G G G F Q S G G N R G R G
Rat Rattus norvegicus P22509 327 34203 S70 G R G G G F Q S G G G R G R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517295 252 27451 R22 R G R G R G G R G G F Q G G K
Chicken Gallus gallus
Frog Xenopus laevis P22232 323 34313 R45 G G F G G R G R G G D R G G R
Zebra Danio Brachydanio rerio NP_998167 317 33615 G40 R G G R G G F G G G F K S P G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1V3 344 34618 G84 R G G G G G R G G G G R G G G
Honey Bee Apis mellifera XP_624378 310 32283 R35 R G G G G G G R G S G R G G G
Nematode Worm Caenorhab. elegans Q22053 352 36364 G39 G G G R G G Y G G G D R G S F
Sea Urchin Strong. purpuratus XP_001175797 311 32878 R56 G G F G G R G R G G P R G R G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FEF8 308 32811 G27 G G G R G F G G G R S F G G G
Baker's Yeast Sacchar. cerevisiae P15646 327 34447 R66 G G S R G G A R G G S R G G R
Red Bread Mold Neurospora crassa Q9HE26 323 33794 R30 R G G R G G A R G G S R G G F
Conservation
Percent
Protein Identity: 100 91.9 77.5 96.8 N.A. 96 95.4 N.A. 71 N.A. 82 81.3 N.A. 76.1 77.5 67.9 80
Protein Similarity: 100 92.2 78.5 96.8 N.A. 96 95.4 N.A. 74.7 N.A. 88.2 86.5 N.A. 81.9 84.1 76.4 85.6
P-Site Identity: 100 100 86.6 93.3 N.A. 80 73.3 N.A. 40 N.A. 46.6 46.6 N.A. 66.6 60 46.6 60
P-Site Similarity: 100 100 86.6 93.3 N.A. 80 73.3 N.A. 46.6 N.A. 53.3 53.3 N.A. 66.6 60 60 60
Percent
Protein Identity: N.A. N.A. N.A. 71.3 66 66.5
Protein Similarity: N.A. N.A. N.A. 78.8 76.4 76.7
P-Site Identity: N.A. N.A. N.A. 46.6 40 53.3
P-Site Similarity: N.A. N.A. N.A. 53.3 46.6 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 13 0 0 44 7 0 0 0 13 7 0 0 13 % F
% Gly: 50 82 75 69 94 44 32 25 100 88 19 0 94 44 69 % G
% His: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 7 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 32 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % P
% Gln: 0 0 0 0 0 0 19 0 0 0 0 7 0 0 0 % Q
% Arg: 50 19 7 32 7 13 7 38 0 7 0 82 0 44 13 % R
% Ser: 0 0 7 0 0 0 0 38 0 7 19 0 7 7 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _
© 2017 Kinexus Bioinformatics Corporation