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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBL
All Species:
51.21
Human Site:
T208
Identified Species:
75.11
UniProt:
P22087
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22087
NP_001427.2
321
33784
T208
I
N
L
A
K
K
R
T
N
I
I
P
V
I
E
Chimpanzee
Pan troglodytes
XP_001135914
299
31246
S193
L
V
Y
A
V
E
F
S
H
R
S
G
R
D
L
Rhesus Macaque
Macaca mulatta
XP_001088664
401
42281
T287
I
N
L
A
K
K
R
T
N
I
I
P
V
I
E
Dog
Lupus familis
XP_533671
313
33300
T200
I
N
L
A
K
K
R
T
N
I
I
P
V
I
E
Cat
Felis silvestris
Mouse
Mus musculus
P35550
327
34288
T214
I
N
L
A
K
K
R
T
N
I
I
P
V
I
E
Rat
Rattus norvegicus
P22509
327
34203
T214
I
N
L
A
K
K
R
T
N
I
I
P
V
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517295
252
27451
I146
H
R
S
G
R
D
L
I
N
V
A
K
K
R
T
Chicken
Gallus gallus
Frog
Xenopus laevis
P22232
323
34313
T210
I
N
V
A
K
K
R
T
N
I
I
P
V
I
E
Zebra Danio
Brachydanio rerio
NP_998167
317
33615
T204
L
N
V
A
K
K
R
T
N
I
I
P
I
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1V3
344
34618
T233
I
N
V
A
K
K
R
T
N
I
I
P
I
I
E
Honey Bee
Apis mellifera
XP_624378
310
32283
T197
I
N
V
A
K
K
R
T
N
I
I
P
I
I
E
Nematode Worm
Caenorhab. elegans
Q22053
352
36364
P239
L
G
V
A
K
K
R
P
N
V
V
P
I
V
E
Sea Urchin
Strong. purpuratus
XP_001175797
311
32878
T199
M
N
V
A
K
K
R
T
N
I
I
P
I
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FEF8
308
32811
T192
V
N
M
A
K
K
R
T
N
V
I
P
I
I
E
Baker's Yeast
Sacchar. cerevisiae
P15646
327
34447
P215
I
S
M
A
K
K
R
P
N
I
I
P
I
I
E
Red Bread Mold
Neurospora crassa
Q9HE26
323
33794
T210
I
N
M
A
T
R
R
T
N
V
I
P
I
V
E
Conservation
Percent
Protein Identity:
100
91.9
77.5
96.8
N.A.
96
95.4
N.A.
71
N.A.
82
81.3
N.A.
76.1
77.5
67.9
80
Protein Similarity:
100
92.2
78.5
96.8
N.A.
96
95.4
N.A.
74.7
N.A.
88.2
86.5
N.A.
81.9
84.1
76.4
85.6
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
6.6
N.A.
93.3
80
N.A.
86.6
86.6
46.6
80
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
20
N.A.
100
100
N.A.
100
100
86.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
71.3
66
66.5
Protein Similarity:
N.A.
N.A.
N.A.
78.8
76.4
76.7
P-Site Identity:
N.A.
N.A.
N.A.
73.3
73.3
60
P-Site Similarity:
N.A.
N.A.
N.A.
100
93.3
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
94
0
0
0
0
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
88
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
7
0
0
0
0
0
0
0
7
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
63
0
0
0
0
0
0
7
0
69
82
0
50
75
0
% I
% Lys:
0
0
0
0
82
82
0
0
0
0
0
7
7
0
0
% K
% Leu:
19
0
32
0
0
0
7
0
0
0
0
0
0
0
7
% L
% Met:
7
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
75
0
0
0
0
0
0
94
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
13
0
0
0
88
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
0
7
7
88
0
0
7
0
0
7
7
0
% R
% Ser:
0
7
7
0
0
0
0
7
0
0
7
0
0
0
0
% S
% Thr:
0
0
0
0
7
0
0
75
0
0
0
0
0
0
7
% T
% Val:
7
7
38
0
7
0
0
0
0
25
7
0
38
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _