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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPS4Y1 All Species: 45.15
Human Site: S204 Identified Species: 70.95
UniProt: P22090 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22090 NP_000999.1 263 29456 S204 N R E R H P G S F D V V H V K
Chimpanzee Pan troglodytes Q861U9 263 29379 S204 N R E R H P G S F D V V H V K
Rhesus Macaque Macaca mulatta NP_001138538 263 29372 S204 N R E R H P G S F D V V H V K
Dog Lupus familis XP_537399 267 29962 S204 N R E K H P G S F D V V H V K
Cat Felis silvestris
Mouse Mus musculus NP_001074505 263 29540 S204 N R E R H P G S F D V V H V K
Rat Rattus norvegicus NP_001103082 262 29180 S204 N R E R H P G S F D V V H V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510806 239 27018 T175 T V Q I D L E T G K I T D F I
Chicken Gallus gallus P47836 263 29576 S204 N R E R H P G S F D V V H V K
Frog Xenopus laevis P49401 263 29646 S204 N R E R H P G S F D V V H V K
Zebra Danio Brachydanio rerio Q642H9 263 29669 S204 N R E K H P G S F D V V H V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P41042 261 29116 P202 V V N R E R H P G S F D I V H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N3X2 259 29025 L200 I I G H R E R L P G A S D I I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays O22424 265 29999 S204 N R E K H K G S F E T I H V E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYK6 262 29797 S204 N R E K H K G S F E T I H I Q
Baker's Yeast Sacchar. cerevisiae P05753 261 29392 D202 I V H K E R H D G G F D L V H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 95.4 90.6 N.A. 87.4 88.2 N.A. 82.1 93.9 93.1 87.8 N.A. 73 N.A. 61.9 N.A.
Protein Similarity: 100 99.6 98 95.1 N.A. 94.3 93.5 N.A. 84.7 96.5 96.1 94.6 N.A. 87 N.A. 77.1 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. 0 100 100 93.3 N.A. 13.3 N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 100 100 100 N.A. 13.3 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. 66 N.A. 66.9 69.5 N.A.
Protein Similarity: N.A. 80.7 N.A. 80.9 82.8 N.A.
P-Site Identity: N.A. 60 N.A. 53.3 6.6 N.A.
P-Site Similarity: N.A. 86.6 N.A. 86.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 0 7 0 60 0 14 14 0 0 % D
% Glu: 0 0 74 0 14 7 7 0 0 14 0 0 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 74 0 14 0 0 7 0 % F
% Gly: 0 0 7 0 0 0 74 0 20 14 0 0 0 0 0 % G
% His: 0 0 7 7 74 0 14 0 0 0 0 0 74 0 14 % H
% Ile: 14 7 0 7 0 0 0 0 0 0 7 14 7 14 14 % I
% Lys: 0 0 0 34 0 14 0 0 0 7 0 0 0 0 60 % K
% Leu: 0 0 0 0 0 7 0 7 0 0 0 0 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 74 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 60 0 7 7 0 0 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 7 % Q
% Arg: 0 74 0 54 7 14 7 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 74 0 7 0 7 0 0 0 % S
% Thr: 7 0 0 0 0 0 0 7 0 0 14 7 0 0 0 % T
% Val: 7 20 0 0 0 0 0 0 0 0 60 60 0 80 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _