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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS4Y1
All Species:
26.97
Human Site:
S217
Identified Species:
42.38
UniProt:
P22090
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22090
NP_000999.1
263
29456
S217
V
K
D
A
N
G
N
S
F
A
T
R
L
S
N
Chimpanzee
Pan troglodytes
Q861U9
263
29379
S217
V
K
D
A
N
G
N
S
F
A
T
R
L
S
N
Rhesus Macaque
Macaca mulatta
NP_001138538
263
29372
S217
V
K
D
A
S
G
N
S
F
A
T
R
I
S
N
Dog
Lupus familis
XP_537399
267
29962
S217
V
K
D
A
N
G
N
S
F
A
T
R
L
S
N
Cat
Felis silvestris
Mouse
Mus musculus
NP_001074505
263
29540
S217
V
K
D
A
S
G
N
S
F
A
T
R
L
S
N
Rat
Rattus norvegicus
NP_001103082
262
29180
G217
V
K
D
A
N
G
N
G
F
A
T
R
L
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510806
239
27018
N188
F
I
K
F
D
T
G
N
L
C
M
V
T
G
G
Chicken
Gallus gallus
P47836
263
29576
S217
V
K
D
A
N
G
N
S
F
A
T
R
L
S
N
Frog
Xenopus laevis
P49401
263
29646
N217
V
K
D
A
N
G
N
N
F
A
T
R
L
S
N
Zebra Danio
Brachydanio rerio
Q642H9
263
29669
S217
V
K
D
S
I
G
N
S
F
A
T
R
L
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P41042
261
29116
G215
V
H
I
K
D
S
Q
G
H
V
F
A
T
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N3X2
259
29025
A213
I
I
H
I
K
D
S
A
G
H
S
F
A
T
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O22424
265
29999
Q217
V
E
D
S
L
G
H
Q
F
A
T
R
M
G
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VYK6
262
29797
E217
I
Q
D
S
T
G
H
E
F
A
T
R
L
G
N
Baker's Yeast
Sacchar. cerevisiae
P05753
261
29392
D215
V
H
I
K
D
S
L
D
N
T
F
V
T
R
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.4
90.6
N.A.
87.4
88.2
N.A.
82.1
93.9
93.1
87.8
N.A.
73
N.A.
61.9
N.A.
Protein Similarity:
100
99.6
98
95.1
N.A.
94.3
93.5
N.A.
84.7
96.5
96.1
94.6
N.A.
87
N.A.
77.1
N.A.
P-Site Identity:
100
100
86.6
100
N.A.
93.3
93.3
N.A.
0
100
93.3
86.6
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
13.3
100
100
93.3
N.A.
13.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
66
N.A.
66.9
69.5
N.A.
Protein Similarity:
N.A.
80.7
N.A.
80.9
82.8
N.A.
P-Site Identity:
N.A.
53.3
N.A.
53.3
6.6
N.A.
P-Site Similarity:
N.A.
80
N.A.
80
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
54
0
0
0
7
0
74
0
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
0
74
0
20
7
0
7
0
0
0
0
0
0
0
% D
% Glu:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% E
% Phe:
7
0
0
7
0
0
0
0
74
0
14
7
0
0
0
% F
% Gly:
0
0
0
0
0
74
7
14
7
0
0
0
0
20
7
% G
% His:
0
14
7
0
0
0
14
0
7
7
0
0
0
0
0
% H
% Ile:
14
14
14
7
7
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
0
60
7
14
7
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
7
0
7
0
7
0
0
0
60
0
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% M
% Asn:
0
0
0
0
40
0
60
14
7
0
0
0
0
0
74
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
7
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
74
0
14
7
% R
% Ser:
0
0
0
20
14
14
7
47
0
0
7
0
0
60
0
% S
% Thr:
0
0
0
0
7
7
0
0
0
7
74
0
20
7
0
% T
% Val:
80
0
0
0
0
0
0
0
0
7
0
14
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _