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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS4Y1
All Species:
38.18
Human Site:
T196
Identified Species:
60
UniProt:
P22090
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22090
NP_000999.1
263
29456
T196
L
G
R
V
G
V
I
T
N
R
E
R
H
P
G
Chimpanzee
Pan troglodytes
Q861U9
263
29379
T196
L
G
R
V
G
V
I
T
N
R
E
R
H
P
G
Rhesus Macaque
Macaca mulatta
NP_001138538
263
29372
T196
L
G
R
V
G
V
I
T
N
R
E
R
H
P
G
Dog
Lupus familis
XP_537399
267
29962
T196
L
G
R
I
G
V
I
T
N
R
E
K
H
P
G
Cat
Felis silvestris
Mouse
Mus musculus
NP_001074505
263
29540
T196
L
G
R
I
G
V
I
T
N
R
E
R
H
P
G
Rat
Rattus norvegicus
NP_001103082
262
29180
T196
L
G
R
I
G
I
I
T
N
R
E
R
H
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510806
239
27018
D167
D
P
L
I
K
V
N
D
T
V
Q
I
D
L
E
Chicken
Gallus gallus
P47836
263
29576
T196
L
G
R
I
G
V
I
T
N
R
E
R
H
P
G
Frog
Xenopus laevis
P49401
263
29646
T196
L
G
R
I
G
V
I
T
N
R
E
R
H
P
G
Zebra Danio
Brachydanio rerio
Q642H9
263
29669
T196
L
G
R
I
G
V
I
T
N
R
E
K
H
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P41042
261
29116
T194
R
N
L
G
R
V
G
T
V
V
N
R
E
R
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N3X2
259
29025
G192
G
R
N
V
G
R
V
G
I
I
G
H
R
E
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O22424
265
29999
K196
T
G
R
V
G
V
I
K
N
R
E
K
H
K
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VYK6
262
29797
K196
R
G
R
V
G
V
I
K
N
R
E
K
H
K
G
Baker's Yeast
Sacchar. cerevisiae
P05753
261
29392
T194
R
N
L
G
R
I
G
T
I
V
H
K
E
R
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.4
90.6
N.A.
87.4
88.2
N.A.
82.1
93.9
93.1
87.8
N.A.
73
N.A.
61.9
N.A.
Protein Similarity:
100
99.6
98
95.1
N.A.
94.3
93.5
N.A.
84.7
96.5
96.1
94.6
N.A.
87
N.A.
77.1
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
93.3
86.6
N.A.
6.6
93.3
93.3
86.6
N.A.
20
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
100
100
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
66
N.A.
66.9
69.5
N.A.
Protein Similarity:
N.A.
80.7
N.A.
80.9
82.8
N.A.
P-Site Identity:
N.A.
73.3
N.A.
73.3
6.6
N.A.
P-Site Similarity:
N.A.
80
N.A.
80
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
74
0
14
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
74
0
14
80
0
14
7
0
0
7
0
0
0
74
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
7
74
0
14
% H
% Ile:
0
0
0
47
0
14
74
0
14
7
0
7
0
0
0
% I
% Lys:
0
0
0
0
7
0
0
14
0
0
0
34
0
14
0
% K
% Leu:
60
0
20
0
0
0
0
0
0
0
0
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
14
7
0
0
0
7
0
74
0
7
0
0
0
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
60
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
20
7
74
0
14
7
0
0
0
74
0
54
7
14
7
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
7
0
0
0
0
0
0
74
7
0
0
0
0
0
0
% T
% Val:
0
0
0
40
0
80
7
0
7
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _