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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPS4Y1 All Species: 6.06
Human Site: T258 Identified Species: 9.52
UniProt: P22090 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22090 NP_000999.1 263 29456 T258 E R D K R L A T K Q S S G _ _
Chimpanzee Pan troglodytes Q861U9 263 29379 T258 E R D K R L A T K Q S S G _ _
Rhesus Macaque Macaca mulatta NP_001138538 263 29372 A258 E R D K R L A A K Q S S G _ _
Dog Lupus familis XP_537399 267 29962 A258 E R D K R L A A K Q S S G Q N
Cat Felis silvestris
Mouse Mus musculus NP_001074505 263 29540 A258 E R D K R L A A K Q N S G _ _
Rat Rattus norvegicus NP_001103082 262 29180
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510806 239 27018 T229 A N G N S F A T R L S N I F V
Chicken Gallus gallus P47836 263 29576 A258 E R D K R L A A K Q S S G _ _
Frog Xenopus laevis P49401 263 29646 A258 E R D K R L A A K Q S S G _ _
Zebra Danio Brachydanio rerio Q642H9 263 29669 A258 E R D K R L A A K Q S S S _ _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P41042 261 29116 L256 A E E R D K R L A A K T H _ _
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N3X2 259 29025 R254 I A E E R D K R M A Q K H _ _
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays O22424 265 29999 A258 E Q R K R D A A A Q A A A N A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYK6 262 29797
Baker's Yeast Sacchar. cerevisiae P05753 261 29392 R256 A E E R D R R R A Q Q G L _ _
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 95.4 90.6 N.A. 87.4 88.2 N.A. 82.1 93.9 93.1 87.8 N.A. 73 N.A. 61.9 N.A.
Protein Similarity: 100 99.6 98 95.1 N.A. 94.3 93.5 N.A. 84.7 96.5 96.1 94.6 N.A. 87 N.A. 77.1 N.A.
P-Site Identity: 100 100 92.3 80 N.A. 84.6 0 N.A. 20 92.3 92.3 84.6 N.A. 0 N.A. 7.6 N.A.
P-Site Similarity: 100 100 92.3 80 N.A. 92.3 0 N.A. 33.3 92.3 92.3 84.6 N.A. 23 N.A. 23 N.A.
Percent
Protein Identity: N.A. 66 N.A. 66.9 69.5 N.A.
Protein Similarity: N.A. 80.7 N.A. 80.9 82.8 N.A.
P-Site Identity: N.A. 33.3 N.A. 0 7.6 N.A.
P-Site Similarity: N.A. 53.3 N.A. 0 23 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 7 0 0 0 0 67 47 20 14 7 7 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 54 0 14 14 0 0 0 0 0 0 0 0 0 % D
% Glu: 60 14 20 7 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 7 0 0 0 0 0 0 0 7 0 % F
% Gly: 0 0 7 0 0 0 0 0 0 0 0 7 47 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 14 0 0 % H
% Ile: 7 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % I
% Lys: 0 0 0 60 0 7 7 0 54 0 7 7 0 0 0 % K
% Leu: 0 0 0 0 0 54 0 7 0 7 0 0 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 7 0 7 0 0 0 0 0 0 7 7 0 7 7 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 7 0 0 0 0 0 0 0 67 14 0 0 7 0 % Q
% Arg: 0 54 7 14 67 7 14 14 7 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 7 0 0 0 0 0 54 54 7 0 0 % S
% Thr: 0 0 0 0 0 0 0 20 0 0 0 7 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 67 67 % _