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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS4Y1
All Species:
55.76
Human Site:
Y149
Identified Species:
87.62
UniProt:
P22090
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22090
NP_000999.1
263
29456
Y149
H
D
A
R
T
I
R
Y
P
D
P
V
I
K
V
Chimpanzee
Pan troglodytes
Q861U9
263
29379
Y149
H
D
A
R
T
I
R
Y
P
D
P
V
I
K
V
Rhesus Macaque
Macaca mulatta
NP_001138538
263
29372
Y149
H
D
A
R
T
I
R
Y
P
D
P
V
I
K
V
Dog
Lupus familis
XP_537399
267
29962
Y149
H
D
A
R
T
I
R
Y
P
D
P
L
I
K
V
Cat
Felis silvestris
Mouse
Mus musculus
NP_001074505
263
29540
Y149
H
D
G
R
T
I
R
Y
P
D
P
L
I
K
V
Rat
Rattus norvegicus
NP_001103082
262
29180
Y149
H
D
A
R
T
I
R
Y
P
D
P
L
I
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510806
239
27018
T124
R
F
A
V
H
R
I
T
A
E
E
A
K
Y
K
Chicken
Gallus gallus
P47836
263
29576
Y149
H
D
A
R
T
I
R
Y
P
D
P
L
I
K
V
Frog
Xenopus laevis
P49401
263
29646
Y149
H
D
A
R
T
I
R
Y
P
D
P
L
I
K
V
Zebra Danio
Brachydanio rerio
Q642H9
263
29669
Y149
H
D
A
R
T
I
R
Y
P
D
P
L
I
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P41042
261
29116
Y149
H
D
G
R
T
I
R
Y
P
D
P
L
I
H
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N3X2
259
29025
Y148
T
D
G
R
T
I
R
Y
P
D
P
H
V
K
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O22424
265
29999
Y149
Y
D
G
R
T
I
R
Y
P
D
P
L
I
K
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VYK6
262
29797
Y149
Y
D
G
R
T
I
R
Y
P
D
P
L
I
K
P
Baker's Yeast
Sacchar. cerevisiae
P05753
261
29392
Y149
H
D
G
R
T
I
R
Y
P
D
P
N
I
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.4
90.6
N.A.
87.4
88.2
N.A.
82.1
93.9
93.1
87.8
N.A.
73
N.A.
61.9
N.A.
Protein Similarity:
100
99.6
98
95.1
N.A.
94.3
93.5
N.A.
84.7
96.5
96.1
94.6
N.A.
87
N.A.
77.1
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
6.6
93.3
93.3
93.3
N.A.
73.3
N.A.
73.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
13.3
100
100
100
N.A.
80
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
66
N.A.
66.9
69.5
N.A.
Protein Similarity:
N.A.
80.7
N.A.
80.9
82.8
N.A.
P-Site Identity:
N.A.
73.3
N.A.
73.3
86.6
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
86.6
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
60
0
0
0
0
0
7
0
0
7
0
0
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
94
0
0
0
0
0
0
0
94
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
40
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
74
0
0
0
7
0
0
0
0
0
0
7
0
7
0
% H
% Ile:
0
0
0
0
0
94
7
0
0
0
0
0
87
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
7
87
7
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
60
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
94
0
94
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
94
0
7
94
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
7
0
0
0
94
0
0
7
0
0
0
0
0
0
0
% T
% Val:
0
0
0
7
0
0
0
0
0
0
0
20
7
0
74
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
14
0
0
0
0
0
0
94
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _