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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GART All Species: 16.36
Human Site: S42 Identified Species: 32.73
UniProt: P22102 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22102 NP_000810.1 1010 107767 S42 G N A G T A C S E K I S N T A
Chimpanzee Pan troglodytes XP_514869 1010 107704 S42 G N A G T A C S E K I S N T A
Rhesus Macaque Macaca mulatta XP_001093303 909 97049 S42 G N A G T A C S E K I S N N A
Dog Lupus familis XP_544864 745 79854
Cat Felis silvestris
Mouse Mus musculus Q64737 1010 107377 A42 G N A G T A G A G K I S N A A
Rat Rattus norvegicus NP_001011899 1010 107561 A42 G N A G T A S A G K I S N A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513896 1008 107242 L42 G N A G T A S L E K I S N A A
Chicken Gallus gallus P21872 1003 106526 S42 G N A G T A N S G K I S N S A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_571692 1017 107609 C42 G N A G T A N C G K I S N S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P00967 1353 144430 V42 G S H G I Q L V E K C R N L D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785897 1012 107051 S42 G N A G T A N S E K I T N M G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P07244 802 86050
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 86.8 66.9 N.A. 85.6 86.5 N.A. 79.8 74.3 N.A. 66.8 N.A. 37.7 N.A. N.A. 58.9
Protein Similarity: 100 99.6 88.5 70.5 N.A. 93.7 93.8 N.A. 89.1 86.7 N.A. 81.3 N.A. 51.9 N.A. N.A. 73.5
P-Site Identity: 100 100 93.3 0 N.A. 73.3 73.3 N.A. 80 80 N.A. 66.6 N.A. 33.3 N.A. N.A. 73.3
P-Site Similarity: 100 100 93.3 0 N.A. 80 80 N.A. 80 86.6 N.A. 73.3 N.A. 40 N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 37.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 52.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 75 0 0 75 0 17 0 0 0 0 0 25 59 % A
% Cys: 0 0 0 0 0 0 25 9 0 0 9 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % D
% Glu: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 84 0 0 84 0 0 9 0 34 0 0 0 0 0 9 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 75 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 84 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 9 9 0 0 0 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 75 0 0 0 0 25 0 0 0 0 0 84 9 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % R
% Ser: 0 9 0 0 0 0 17 42 0 0 0 67 0 17 0 % S
% Thr: 0 0 0 0 75 0 0 0 0 0 0 9 0 17 0 % T
% Val: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _