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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNXB All Species: 2.73
Human Site: T3997 Identified Species: 7.5
UniProt: P22105 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22105 NP_061978.6 4289 464325 T3997 T P R T A L L T W T E P P V R
Chimpanzee Pan troglodytes XP_001156720 2201 240780 S1923 G Y L L V Y E S V D G T V K E
Rhesus Macaque Macaca mulatta XP_001099317 2201 241036 S1923 G Y L L V Y E S V D G T V K E
Dog Lupus familis XP_538811 2201 240437 S1923 G Y L L V Y E S V D G T V K E
Cat Felis silvestris
Mouse Mus musculus Q80YX1 2110 231789 S1832 G Y L L V Y E S V D G T V K E
Rat Rattus norvegicus NP_446313 2019 221600 S1741 G Y L L V Y E S V D G T V K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508028 1806 197176 S1528 G Y L L I Y Q S V D G T I K E
Chicken Gallus gallus P10039 1808 198841 S1530 D Y L L T Y E S I D G R V K E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_570982 1710 186188 S1432 G Y I L S F E S A D G V V K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.6 25.2 24.8 N.A. 23.7 22.9 N.A. 21.9 22.2 N.A. 20.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 35.2 35 34.9 N.A. 33.8 32.9 N.A. 30.3 30.2 N.A. 29 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 0 0 N.A. 0 0 N.A. 0 0 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 6.6 6.6 N.A. 6.6 6.6 N.A. 6.6 6.6 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 12 0 0 0 12 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 0 0 0 0 0 0 0 89 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 78 0 0 0 12 0 0 0 89 % E
% Phe: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % F
% Gly: 78 0 0 0 0 0 0 0 0 0 89 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 0 12 0 0 0 12 0 0 0 12 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 89 0 % K
% Leu: 0 0 78 89 0 12 12 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 12 0 0 0 0 0 0 0 0 0 12 12 0 0 % P
% Gln: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 12 0 0 0 0 0 0 0 0 12 0 0 12 % R
% Ser: 0 0 0 0 12 0 0 89 0 0 0 0 0 0 0 % S
% Thr: 12 0 0 12 12 0 0 12 0 12 0 67 0 0 0 % T
% Val: 0 0 0 0 56 0 0 0 67 0 0 12 78 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % W
% Tyr: 0 89 0 0 0 78 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _